| Nexdine, LLC | Accommodation and Food Services | $5,160,000 | $5,219,093 | 391 | $73.0M |  Research |
| Lockwood/mckinnon Company Inc. | Accommodation and Food Services | $3,652,734 | $3,694,842 | 500 | $88.8M | Research |
| New England Controls INC | Transportation and Warehousing | $3,530,800 | $3,571,502 | 210 | $16.3M | Research |
| Hub Folding Box Company INC | Manufacturing | $3,075,929 | $2,946,649 | 216 | $214.2M | Research |
| Nexdine LLC | Accommodation and Food Services | $2,000,000 | $2,015,014 | 150 | $28.0M | Research |
| Triton Technologies INC | Administrative and Support and Waste Management | $1,996,600 | $2,018,754 | 275 | $52.0M | Research |
| Milton's Distributing Co., INC | Wholesale Trade | $1,390,200 | $1,401,437 | 116 | $29.9M | Research |
| Merrimack Valley Emergency Associates | Health Care and Social Assistance | $1,387,000 | $1,404,183 | 85 | $19.7M | Research |
| Merrimack Valley Emergency Associates | Health Care and Social Assistance | $1,379,200 | $1,392,647 | 85 | $26.7M | Research |
| Next-Gen Supply Group Inc. | Manufacturing | $1,353,160 | $1,369,323 | 80 | $79.3M | Research |
| Proven Process Medical Devices, Inc. | Manufacturing | $1,342,077 | $1,354,321 | 89 | $23.3M | Research |
| Intransit Container INC | Construction | $1,258,065 | $1,269,405 | 90 | $102.5M | Research |
| Chex Finer Foods Inc. | Wholesale Trade | $1,228,000 | $1,235,027 | 92 | $23.7M | Research |
| Controlled Environment S | Transportation and Warehousing | $1,192,025 | $1,200,038 | 66 | $16.7M | Research |
| Controlled Environment Systems, LLC | Transportation and Warehousing | $1,159,292 | $1,169,273 | 60 | $15.2M | Research |
| Clinical Science Laboratory, Inc. | Health Care and Social Assistance | $897,600 | $903,260 | 98 | $22.7M | Research |
| Lowell Anesthesiology | Health Care and Social Assistance | $832,200 | $839,436 | 39 | $12.2M | Research |
| Metrowest Emergency Physicians, Inc. | Health Care and Social Assistance | $721,357 | $730,394 | 37 | $11.6M | Research |
| Metrowest Emergency Physicians Inc. | Health Care and Social Assistance | $696,165 | $700,456 | 23 | <$5M | Research |
| Creative Services, Inc. | Administrative and Support and Waste Management | $675,368 | $680,197 | 52 | $7.6M | Research |
| Creative Services INC | Administrative and Support and Waste Management | $675,367 | $679,012 | 54 | $7.9M | Research |
| Visiting Rehab and Nursing Services, Inc. | Health Care and Social Assistance | $655,400 | $660,661 | 72 | $11.7M | Research |
| Bristol Builders and Contractors Inc. | Construction | $650,000 | $656,340 | 32 | $10.1M | Research |
| Bristol Builders and Contractors, Inc. | Construction | $650,000 | $655,663 | 38 | $12.0M | Research |
| R.h. Scales Co INC | Wholesale Trade | $625,965 | $631,607 | 40 | $12.3M | Research |