| Community Health Center of Cape Cod INC | Health Care and Social Assistance | $2,390,000 | $2,421,336 | 166 | N/A |  Research |
| Black Dog Tavern Company LLC | Accommodation and Food Services | $1,586,074 | $1,606,825 | 149 | $26.5M | Research |
| Bobby Byrnes Management Corp | Accommodation and Food Services | $1,281,381 | $1,290,422 | 110 | $19.5M | Research |
| Southworth Willowbend LLC | Arts, Entertainment, and Recreation | $1,218,900 | $1,234,428 | 69 | $9.7M | Research |
| Botello Lumber Company INC | Retail Trade | $1,114,250 | $1,129,107 | 87 | $18.0M | Research |
| Maffei Landscape Holdings, LLC | Finance and Insurance | $868,400 | $873,755 | 60 | $30.8M | Research |
| Mashpee Acquisition, LLC | Health Care and Social Assistance | $856,787 | $866,426 | 131 | $22.3M | Research |
| Mashpee Acquisition LLC | Health Care and Social Assistance | $856,787 | $864,308 | 131 | $22.3M | Research |
| Bobby Byrne's Manangement Corporation | Accommodation and Food Services | $812,500 | $818,977 | 165 | $29.3M | Research |
| New England Discount Retailers, INC | Retail Trade | $519,800 | $522,644 | 80 | $12.5M | Research |
| Carroll Physical Therapy | Health Care and Social Assistance | $447,500 | $452,684 | 40 | $10.8M | Research |
| Carroll Physical Therapy | Health Care and Social Assistance | $430,000 | $433,918 | 42 | $11.3M | Research |
| Bleu INC | Accommodation and Food Services | $405,734 | $409,915 | 21 | <$5M | Research |
| Better Food, LLC | Accommodation and Food Services | $388,930 | $394,537 | 21 | <$5M | Research |
| Bleu, Inc. | Accommodation and Food Services | $336,913 | $340,066 | 36 | $6.4M | Research |
| Franey Medical Laboratories INC | Health Care and Social Assistance | $325,474 | $222,068 | 28 | $6.5M | Research |
| Agm Marine Contractors, Inc. | Construction | $317,359 | $319,589 | 16 | $6.0M | Research |
| Hyannis Family Medical Care | Health Care and Social Assistance | $300,000 | $407,280 | 20 | <$5M | Research |
| New Image Landscapes LLC | Administrative and Support and Waste Management | $298,700 | $300,924 | 34 | $7.4M | Research |
| New Image Landscapes LLC | Administrative and Support and Waste Management | $298,700 | $300,857 | 27 | $5.8M | Research |
| Fraser Construction Company, Inc. | Construction | $297,500 | $299,640 | 25 | $8.2M | Research |
| Briggs Landscape Construction Inc. | Administrative and Support and Waste Management | $271,400 | $274,589 | 32 | $6.9M | Research |
| Applied Coastal Research & Eng | Professional, Scientific, and Technical Services | $256,100 | $256,622 | 11 | <$5M | Research |
| Mashpee Commons Limited Partnership | Real Estate and Rental and Leasing | $253,300 | $255,172 | 14 | <$5M | Research |
| Better Food, LLC | Accommodation and Food Services | $252,052 | $255,434 | 24 | <$5M | Research |