| Charles River Association for Retarded Citizens, Inc. | Health Care and Social Assistance | $3,043,325 | $3,078,344 | 407 | N/A | Research |
| Walker | Educational Services | $2,962,400 | $2,999,816 | 313 | N/A | Research |
| Acceleration Partners, LLC | Professional, Scientific, and Technical Services | $2,275,500 | $2,301,731 | 139 | $15.6M | Research |
| Cambridge Healthtech Ins | Administrative and Support and Waste Management | $2,000,000 | $2,026,667 | 132 | $25.0M | Research |
| Convergent Dental, INC | Manufacturing | $1,986,908 | $2,007,715 | 102 | $28.5M | Research |
| Chartwell Management LLC | Real Estate and Rental and Leasing | $1,971,500 | $1,993,754 | 155 | $23.3M | Research |
| Chestnut Dental Associates, P.c. | Health Care and Social Assistance | $1,833,365 | $1,845,398 | 155 | $35.9M | Research |
| Chestnut Dental Associates PC | Health Care and Social Assistance | $1,817,722 | $1,825,851 | 150 | $34.8M | Research |
| Convergent Dental INC | Manufacturing | $1,798,546 | $1,812,435 | 84 | $23.5M | Research |
| Muzi Motors INC | Retail Trade | $1,566,592 | $1,580,112 | 136 | $34.3M | Research |
| Senior Residential Care Kingston, Inc. | Health Care and Social Assistance | $1,553,690 | $1,570,759 | 209 | $35.6M | Research |
| Shamrock Painting | Construction | $1,481,200 | $21,146 | 1 | <$5M | Research |
| Syrinx Consulting Corp | Professional, Scientific, and Technical Services | $1,359,880 | $1,368,524 | 60 | $12.4M | Research |
| Strategic Solutions Group LLC | Information | $1,130,500 | $1,137,673 | 48 | $8.1M | Research |
| Kriss Law LLC | Professional, Scientific, and Technical Services | $1,128,200 | $1,141,213 | 82 | $19.9M | Research |
| Wingate at Needham INC | Health Care and Social Assistance | $1,126,905 | $1,139,286 | 118 | $20.1M | Research |
| Wingate of Ulster, Inc. | Health Care and Social Assistance | $1,040,692 | $1,052,097 | 136 | $23.1M | Research |
| Wingate Healthcare, Inc. | Health Care and Social Assistance | $954,757 | $979,267 | 44 | $7.5M | Research |
| Advantage Nursing Care | Health Care and Social Assistance | $949,200 | $954,271 | 321 | $55.0M | Research |
| Src Chestnut Hill Snf LLC | Health Care and Social Assistance | $929,597 | $939,810 | 101 | $17.2M | Research |
| Three Limes, Inc. | Accommodation and Food Services | $909,800 | $923,559 | 61 | $10.8M | Research |
| C4 Innovations, LLC | Professional, Scientific, and Technical Services | $844,125 | $855,133 | 56 | $11.6M | Research |
| C4 Innovations LLC | Health Care and Social Assistance | $844,125 | $855,434 | 50 | $8.1M | Research |
| Whc Haverhill INC | Health Care and Social Assistance | $836,855 | $846,049 | 107 | $18.2M | Research |
| Nauset Construction Corporation | Construction | $805,600 | $810,389 | 48 | $14.6M | Research |