| Cambridge Healthtech Institute, Inc. | Administrative and Support and Waste Management | $3,256,275 | $3,294,808 | 170 | $32.2M |  Research |
| Gearscrm, Inc. | Professional, Scientific, and Technical Services | $2,093,100 | $2,122,977 | 105 | $10.9M | Research |
| Bakers' Best INC | Accommodation and Food Services | $2,000,000 | $2,018,389 | 179 | $33.4M | Research |
| Schernecker Property Services, Inc. | Construction | $1,954,907 | $1,976,031 | 76 | $23.1M | Research |
| Kaminario INC | Professional, Scientific, and Technical Services | $1,688,305 | $1,576,313 | 57 | $11.8M | Research |
| Aaa Airporter Services INC | Transportation and Warehousing | $1,610,450 | $1,623,334 | 118 | $8.2M | Research |
| Safety Net Access Inc. | Information | $1,600,000 | $1,611,867 | 77 | $12.9M | Research |
| The Counseling and Psychotherapy Center of Greater Boston, I | Health Care and Social Assistance | $1,542,550 | $1,558,275 | 123 | $28.8M | Research |
| Clearedge Partners, Inc. | Professional, Scientific, and Technical Services | $1,523,500 | $1,474,837 | 90 | $28.6M | Research |
| Safety Netaccess Inc. | Professional, Scientific, and Technical Services | $1,500,000 | $1,517,219 | 79 | $16.3M | Research |
| Syrinx Consulting Corp | Professional, Scientific, and Technical Services | $1,359,880 | $1,374,559 | 51 | $10.5M | Research |
| Westwood Cartage INC | Transportation and Warehousing | $1,335,399 | $1,345,749 | 133 | $20.1M | Research |
| Platformq, LLC | Arts, Entertainment, and Recreation | $1,299,923 | $1,313,883 | 54 | $6.0M | Research |
| Bakers Best, Inc. | Accommodation and Food Services | $1,230,302 | $1,457,173 | 139 | $25.9M | Research |
| Kaplansky Insurance Agency, INC | Finance and Insurance | $1,224,600 | $1,235,281 | 76 | $39.0M | Research |
| Strategic Solutions Group LLC | Information | $1,130,500 | $1,136,509 | 42 | $7.1M | Research |
| Bowdoin Construction Corp | Construction | $1,125,000 | $1,139,813 | 48 | $54.7M | Research |
| Steelco Chain Link Fence Erecting Co INC | Construction | $924,100 | $936,126 | 41 | $14.0M | Research |
| Community Broadcasters, LLC | Information | $922,925 | $929,550 | 68 | $11.4M | Research |
| Src Harwich LLC | Health Care and Social Assistance | $920,615 | $930,728 | 100 | $17.0M | Research |
| Temple Beth Shalom | Other Services (except Public Administration) | $871,000 | $879,831 | 218 | N/A | Research |
| Nauset Construction Corp | Construction | $805,600 | $814,473 | 33 | $37.6M | Research |
| Src Weston, LLC | Health Care and Social Assistance | $767,412 | $787,112 | 80 | $13.6M | Research |
| Medminder Systems, Inc. | Retail Trade | $686,400 | $692,606 | 83 | $14.5M | Research |
| Bulfinch Group Insurance Agency LLC | Finance and Insurance | $648,600 | $608,093 | 51 | $26.2M | Research |