| Collaborative for Educational Services, Inc. | Educational Services | $5,825,000 | $5,909,742 | 478 | N/A |  Research |
| Viability INC | Health Care and Social Assistance | $3,604,815 | $3,334,793 | 410 | N/A | Research |
| Nonotuck Resource Associates, INC | Health Care and Social Assistance | $2,441,306 | $0 | 241 | N/A | Research |
| The Clarke School for the Deaf, Inc. | Educational Services | $1,608,187 | $1,629,853 | 136 | N/A | Research |
| Cutchins Programs for Children & Families, INC | Educational Services | $1,522,400 | $1,138,119 | 153 | N/A | Research |
| River Valley Market, LLC | Retail Trade | $1,329,900 | $1,338,827 | 147 | $36.7M | Research |
| Communicatehealth, Inc. | Professional, Scientific, and Technical Services | $1,273,141 | $1,292,883 | 82 | $11.5M | Research |
| Baroco Corporation | Health Care and Social Assistance | $1,175,008 | $1,178,292 | 159 | $25.8M | Research |
| Checkwriters, Inc. | Professional, Scientific, and Technical Services | $1,015,500 | $1,023,207 | 63 | $20.1M | Research |
| Machinemetrics, Inc. | Manufacturing | $933,000 | $943,608 | 47 | $11.5M | Research |
| Wright Architectural Millwork Corp | Manufacturing | $856,195 | $861,023 | 52 | $51.6M | Research |
| Wright Architectural Millwork Corp | Manufacturing | $830,338 | $833,820 | 53 | $13.9M | Research |
| Mananto Enterprises LLC | Accommodation and Food Services | $750,117 | $757,431 | 115 | $36.0M | Research |
| Baroco Corporation | Health Care and Social Assistance | $750,000 | $753,719 | 81 | $13.1M | Research |
| Pioneer Valley Educational Press, Inc. | Information | $735,920 | $740,174 | 45 | $7.6M | Research |
| Ltl Automotive LLC | Retail Trade | $714,112 | $723,953 | 57 | $14.4M | Research |
| Ltl Automotive LLC | Retail Trade | $714,112 | $720,764 | 53 | $13.4M | Research |
| Webber & Grinnell Insurance Agency, Inc. | Finance and Insurance | $696,600 | $539,436 | 47 | $24.1M | Research |
| Johnson & Hill Staffing Services Inc. | Administrative and Support and Waste Management | $696,264 | $700,747 | 87 | $13.7M | Research |
| Pioneer Valley Educational Press Inc. | Retail Trade | $660,463 | $665,168 | 54 | $13.5M | Research |
| Northampton Area Pediatrics LLP | Health Care and Social Assistance | $650,068 | $653,558 | 55 | $17.3M | Research |
| Brewster Court Pub Inc. | Accommodation and Food Services | $629,906 | $634,030 | 82 | $14.6M | Research |
| Lia Northampton Inc. | Retail Trade | $606,917 | $612,704 | 41 | $10.3M | Research |
| Lia Northampton INC | Retail Trade | $606,900 | $615,131 | 56 | $14.1M | Research |
| Hampshire Regional Young Men's Christian Association | Arts, Entertainment, and Recreation | $597,500 | $546,579 | 192 | N/A | Research |