| Judge Baker Children's Cener | Professional, Scientific, and Technical Services | $2,449,000 | $1,913,408 | 210 | N/A | Research |
| Edgar P Benjamin Healthcare | Health Care and Social Assistance | $1,600,000 | $1,609,445 | 180 | $30.6M | Research |
| Sociedad Latina Inc. | Other Services (except Public Administration) | $499,840 | $295,749 | 44 | N/A | Research |
| Squashbusters, Inc. | Educational Services | $427,750 | $382,467 | 26 | N/A | Research |
| Squashbusters Inc. | Educational Services | $375,597 | $380,501 | 32 | N/A | Research |
| Commonwealth Land Trust, Inc. | Real Estate and Rental and Leasing | $375,000 | $411,590 | 40 | N/A | Research |
| Roxbury Youthworks Inc. | Health Care and Social Assistance | $319,375 | $321,664 | 32 | $5.2M | Research |
| Our Lady of Perpetual Help School | Other Services (except Public Administration) | $307,900 | $310,928 | 37 | N/A | Research |
| New England Design & Construction, Inc. | Construction | $302,595 | $305,503 | 15 | <$5M | Research |
| Whittier Health Pharmacy, Inc. | Retail Trade | $226,000 | $207,958 | 15 | <$5M | Research |
| Smart From the Start INC | Administrative and Support and Waste Management | $225,333 | $227,298 | 29 | N/A | Research |
| The Islamic Society of Boston | Other Services (except Public Administration) | $195,000 | $196,165 | 16 | N/A | Research |
| Smart From the Start, Inc. | Administrative and Support and Waste Management | $179,534 | $180,721 | 25 | N/A | Research |
| The Islamic Society of Boston | Other Services (except Public Administration) | $170,000 | $172,296 | 24 | N/A | Research |
| Orthopaedic Clinical Assoc INC | Health Care and Social Assistance | $159,672 | $159,273 | 9 | <$5M | Research |
| Chima Ohaegbulam, Md, PC | Health Care and Social Assistance | $108,148 | $109,627 | 6 | <$5M | Research |
| Boston Bldg Materials Co Op | Other Services (except Public Administration) | $100,265 | $101,240 | 11 | N/A | Research |
| Carl T. Talmo M.d. P.c. | Health Care and Social Assistance | $97,720 | $99,184 | 5 | <$5M | Research |
| 1625 Exchange INC | Accommodation and Food Services | $96,750 | $97,381 | 12 | <$5M | Research |
| Carl T. Talmo, M.d., P.c. | Health Care and Social Assistance | $91,649 | $92,751 | 5 | <$5M | Research |
| Galleon Ventures INC | Accommodation and Food Services | $90,707 | $92,479 | 12 | <$5M | Research |
| Boston Building Materials Co-Op INC | Other Services (except Public Administration) | $81,850 | $82,646 | 10 | N/A | Research |
| Kitty O Sheas INC | Accommodation and Food Services | $81,832 | $82,404 | 22 | <$5M | Research |
| Center for Computer Assisted & Reconstructive Surgery, Inc. | Health Care and Social Assistance | $81,750 | $66,247 | 5 | <$5M | Research |
| James V Bono MD PC | Health Care and Social Assistance | $80,145 | $81,100 | 5 | <$5M | Research |