| William B Rice Eventide Home | Health Care and Social Assistance | $1,531,501 | $913,279 | 73 | N/A | Research |
| Alvin Hollis & Co., Inc. | Retail Trade | $1,128,333 | $1,138,363 | 57 | $13.6M | Research |
| South Shore Radiological Associates, Inc. | Health Care and Social Assistance | $861,400 | $871,383 | 27 | $5.4M | Research |
| U S Air Conditioning-Heating, Inc. | Construction | $856,418 | $503,553 | 22 | $7.2M | Research |
| South Suburban Gastroenterology | Health Care and Social Assistance | $626,550 | $633,983 | 49 | $15.4M | Research |
| Morton Donut INC | Accommodation and Food Services | $566,328 | $568,546 | 82 | $14.6M | Research |
| Good Brothers Dodge Inc. | Retail Trade | $471,900 | $477,130 | 30 | $7.6M | Research |
| Dentistry for Children, P.c. | Health Care and Social Assistance | $455,262 | $461,623 | 44 | $10.2M | Research |
| Dentistry for Children P C | Health Care and Social Assistance | $455,260 | $459,788 | 44 | $10.2M | Research |
| Morton Donut Inc. | Accommodation and Food Services | $444,165 | $408,689 | 91 | $16.2M | Research |
| South Shore Cardiology P.c. | Health Care and Social Assistance | $401,222 | $404,566 | 40 | $12.6M | Research |
| South Shore Cardiology P.c. | Health Care and Social Assistance | $401,200 | $404,833 | 29 | $5.8M | Research |
| Air Control Systems, Inc. | Construction | $386,149 | $442,958 | 39 | $12.3M | Research |
| New England Eye Surgical Center, INC | Health Care and Social Assistance | $318,100 | $320,574 | 17 | <$5M | Research |
| Yogi Raj Corp | Retail Trade | $307,946 | $311,128 | 89 | $13.6M | Research |
| Ees Silver LLC | Health Care and Social Assistance | $272,700 | $275,741 | 19 | <$5M | Research |
| St. Francis Xavier School | Educational Services | $232,700 | $235,234 | 21 | N/A | Research |
| New England Wildlife Cen | Other Services (except Public Administration) | $217,976 | $219,489 | 27 | N/A | Research |
| New England Wildlife Center, Inc. | Other Services (except Public Administration) | $214,820 | $216,324 | 31 | N/A | Research |
| Alltech Building Systems INC | Administrative and Support and Waste Management | $205,775 | $206,931 | 17 | <$5M | Research |
| South Shore Allergy & Asthma Specialists, PC | Health Care and Social Assistance | $200,400 | $202,069 | 15 | <$5M | Research |
| South Shore Allergy and Asthma Specialist, PC | Health Care and Social Assistance | $193,873 | $195,233 | 13 | <$5M | Research |
| Oasis Day Spa, Inc. | Other Services (except Public Administration) | $188,075 | $189,919 | 35 | $6.7M | Research |
| South Shore Plastic Surgery INC | Health Care and Social Assistance | $187,800 | $189,446 | 15 | <$5M | Research |
| Larry D. Burt Dmd PC | Health Care and Social Assistance | $183,980 | $184,977 | 13 | <$5M | Research |