| Behavioral Health Network Inc. | Health Care and Social Assistance | $10,000,000 | $10,081,370 | 500 | $117.1M | Research |
| Harry Grodsky & Co INC | Construction | $8,255,687 | $8,425,324 | 135 | $42.7M | Research |
| Peter Pan Bus Lines INC | Transportation and Warehousing | $6,162,100 | $6,254,874 | 493 | $189.5M | Research |
| American International College | Educational Services | $4,559,800 | $4,612,111 | 476 | N/A | Research |
| The Futures Healthcore, LLC | Health Care and Social Assistance | $4,403,595 | $4,454,481 | 485 | $130.9M | Research |
| Mass Park, Inc. | Other Services (except Public Administration) | $3,700,000 | $3,743,372 | 500 | $95.5M | Research |
| United Personnel Services, Inc. | Administrative and Support and Waste Management | $3,544,070 | $3,590,483 | 303 | $47.7M | Research |
| New England Orthopedic Surgeons, INC | Health Care and Social Assistance | $3,326,537 | $3,363,591 | 228 | $71.6M | Research |
| The Republican Company | Information | $2,649,857 | $2,684,265 | 225 | $37.8M | Research |
| Rocky's Hardware, Inc. | Retail Trade | $2,640,000 | $2,670,378 | 486 | $100.3M | Research |
| Caring Health Center INC | Health Care and Social Assistance | $2,630,892 | $1,962,012 | 260 | $46.3M | Research |
| Way Finders, Inc. | Public Administration | $2,500,000 | $2,721,649 | 227 | N/A | Research |
| Complete Payroll Solutions, LLC | Professional, Scientific, and Technical Services | $2,310,000 | $2,337,214 | 121 | $38.5M | Research |
| Thing5, LLC | Administrative and Support and Waste Management | $2,061,780 | $0 | 118 | $22.3M | Research |
| Peter Pan Bus Lines INC | Transportation and Warehousing | $2,000,000 | $2,010,500 | 126 | $48.4M | Research |
| Falcon Hotel Corp | Accommodation and Food Services | $1,902,172 | $1,914,575 | 173 | $54.1M | Research |
| Pioneer Valley Cardiology P.c. | Health Care and Social Assistance | $1,805,500 | $1,816,086 | 160 | $50.2M | Research |
| M. L. Schmitt, INC | Construction | $1,727,637 | $1,746,257 | 50 | $16.5M | Research |
| New England Dermatology PC | Health Care and Social Assistance | $1,564,297 | $1,570,728 | 112 | $35.2M | Research |
| New England Dermatology PC | Health Care and Social Assistance | $1,564,297 | $1,581,591 | 113 | $35.5M | Research |
| Bacon Wilson, P.c. | Professional, Scientific, and Technical Services | $1,551,240 | $1,559,825 | 101 | $24.5M | Research |
| M. L. Schmitt Inc. | Construction | $1,543,695 | $1,550,384 | 47 | $15.5M | Research |
| J.d. Rivet & Co. Inc. | Construction | $1,506,457 | $1,515,579 | 101 | $33.3M | Research |
| Pathlight INC | Health Care and Social Assistance | $1,500,000 | $1,513,192 | 500 | $85.1M | Research |
| Astro Chemicals, Inc. | Wholesale Trade | $1,448,100 | $1,456,869 | 74 | $19.0M | Research |