| Methods Machine Tools INC | Manufacturing | $7,468,113 | $7,553,842 | 323 | $84.6M | Research |
| Cavicchio Greenhouses, Inc. | Agriculture, Forestry, Fishing and Hunting | $4,163,217 | $4,211,465 | 235 | $24.0M | Research |
| Jbk Management LLC | Accommodation and Food Services | $3,304,400 | $3,349,927 | 500 | $88.8M | Research |
| Connexion Systems and Engineering, Inc. | Administrative and Support and Waste Management | $2,516,500 | $2,545,181 | 209 | $32.9M | Research |
| Adtech Systems LLC | Construction | $2,135,300 | $2,159,871 | 111 | $36.5M | Research |
| Adtech Systems LLC | Wholesale Trade | $2,000,000 | $2,019,178 | 87 | $26.7M | Research |
| Advocates for Human Potential INC | Professional, Scientific, and Technical Services | $1,841,562 | $1,858,238 | 105 | $10.9M | Research |
| Dsd Laboratories, Inc. | Professional, Scientific, and Technical Services | $1,680,400 | $1,465,015 | 71 | $14.7M | Research |
| Herb Chambers Boston Post Road INC | Retail Trade | $1,649,005 | $1,667,709 | 129 | $32.5M | Research |
| Advocates for Human Potential, Inc. | Professional, Scientific, and Technical Services | $1,638,812 | $1,653,197 | 102 | $10.6M | Research |
| Lynch Landscape & Tree Service, Inc. | Professional, Scientific, and Technical Services | $1,277,035 | $1,287,916 | 95 | $19.2M | Research |
| A Blade of Grass LLC | Professional, Scientific, and Technical Services | $1,194,617 | $1,203,814 | 67 | $13.5M | Research |
| Sudbury Pines Extended Care Facility Inc. | Health Care and Social Assistance | $1,177,825 | $1,190,879 | 115 | $19.6M | Research |
| Bear Mt Sudbury LLC | Health Care and Social Assistance | $1,009,800 | $1,023,190 | 74 | $12.6M | Research |
| Herb Chambers of Sudbury INC | Retail Trade | $885,728 | $892,886 | 68 | $17.1M | Research |
| Evolution Sports Science Holdings LLC | Arts, Entertainment, and Recreation | $695,200 | $0 | 95 | $13.3M | Research |
| The Wayside Inn | Accommodation and Food Services | $691,299 | $697,530 | 59 | N/A | Research |
| Ti-Sales INC | Wholesale Trade | $596,000 | $589,982 | 28 | $8.6M | Research |
| Ti-Sales INC | Utilities | $551,952 | $556,534 | 35 | N/A | Research |
| Camp Sewataro LLC | Arts, Entertainment, and Recreation | $535,410 | $540,383 | 160 | $22.4M | Research |
| The Wayside Inn | Accommodation and Food Services | $481,900 | $486,363 | 110 | N/A | Research |
| P-Fit Development, LLC | Arts, Entertainment, and Recreation | $477,800 | $95,864 | 120 | $16.8M | Research |
| Willow Hill School, INC | Educational Services | $457,700 | $460,332 | 29 | N/A | Research |
| Cavanaugh Tocci Associates, Inc. | Professional, Scientific, and Technical Services | $430,000 | $434,559 | 18 | <$5M | Research |
| Convenient Homecare Services INC | Health Care and Social Assistance | $417,227 | $419,387 | 82 | $14.0M | Research |