| Open Sky Community Services | Health Care and Social Assistance | $10,000,000 | $10,128,889 | 500 | $85.1M |  Research |
| Seven Hills Foundation Inc. | Health Care and Social Assistance | $10,000,000 | $10,092,329 | 500 | $85.1M | Research |
| Greenwood Industries INC | Construction | $8,735,000 | $7,604,694 | 354 | $120.6M | Research |
| Assumption College | Educational Services | $7,500,000 | $7,632,708 | 429 | N/A | Research |
| Family Health Center of Worcester, Inc. | Health Care and Social Assistance | $5,927,345 | $5,996,849 | 439 | N/A | Research |
| Masis Staffing Solutions LLC | Administrative and Support and Waste Management | $5,000,000 | $7,600,625 | 499 | $78.5M | Research |
| Expert Staffing Partners, Inc. | Professional, Scientific, and Technical Services | $5,000,000 | $5,056,712 | 500 | $51.8M | Research |
| Ostrow Electrical Company INC | Construction | $4,828,000 | $3,904,958 | 149 | $49.0M | Research |
| The Jewish Healthcare Center, Inc. | Health Care and Social Assistance | $4,159,000 | $4,219,652 | 316 | N/A | Research |
| Edward M. Kennedy Community Health Center, Inc. | Health Care and Social Assistance | $3,967,633 | $4,022,626 | 359 | N/A | Research |
| Pieco Holding, INC | Manufacturing | $3,884,620 | $3,927,782 | 351 | $123.9M | Research |
| Becker College | Educational Services | $3,308,139 | $3,347,565 | 284 | N/A | Research |
| Notre Dame Health Care Center, Inc. | Health Care and Social Assistance | $3,281,700 | $3,320,811 | 298 | N/A | Research |
| S & S Staffing, LLC | Administrative and Support and Waste Management | $3,047,500 | $3,081,482 | 461 | $72.5M | Research |
| Worcester Academy | Educational Services | $2,559,200 | $2,589,560 | 170 | N/A | Research |
| Ballard Mack Business Trust | Other Services (except Public Administration) | $2,523,700 | $2,552,863 | 150 | $29.4M | Research |
| Ascentria Community Services Inc. | Health Care and Social Assistance | $2,518,900 | $2,534,842 | 468 | $75.8M | Research |
| Guild of St. Agnes of Worcester, Inc. | Health Care and Social Assistance | $2,493,100 | $2,521,515 | 319 | N/A | Research |
| Roman Catholic Bishop of Worcester | Other Services (except Public Administration) | $2,386,700 | $2,413,749 | 226 | N/A | Research |
| The Young Mens Chrsitian Association of Central Massachusett | Health Care and Social Assistance | $2,352,975 | $2,383,694 | 279 | N/A | Research |
| Carroll Enterprises, Inc. | Finance and Insurance | $2,224,300 | $2,248,458 | 142 | $73.0M | Research |
| Easter Seals Massachusetts, INC | Other Services (except Public Administration) | $2,156,300 | $2,190,624 | 181 | N/A | Research |
| Cogswell Sprinkler Co. Inc. | Construction | $2,084,000 | $2,090,876 | 119 | $38.0M | Research |
| Commonwealth Electrical Technologies, Inc. | Construction | $2,062,000 | $2,086,057 | 121 | $39.8M | Research |
| Niche Operations INC | Accommodation and Food Services | $2,000,000 | $2,021,534 | 195 | $34.6M | Research |