| International Fund for Animal Welfare INC | Other Services (except Public Administration) | $3,066,543 | $3,103,762 | 176 | N/A | Research |
| Dennis East International, LLC | Wholesale Trade | $672,500 | $527,570 | 21 | $6.4M | Research |
| Wingate Kirkland Operating | Accommodation and Food Services | $578,662 | $586,256 | 50 | $15.6M | Research |
| 1696corp | Accommodation and Food Services | $403,564 | $405,571 | 30 | $5.3M | Research |
| Habitat for Humanity of Cape Cod, Inc. | Other Services (except Public Administration) | $298,500 | $302,107 | 29 | $5.5M | Research |
| Habitat for Humanity of Cape Cod Inc. | Health Care and Social Assistance | $296,920 | $299,535 | 25 | <$5M | Research |
| Oliver Ormon INC | Accommodation and Food Services | $296,461 | $299,466 | 45 | $8.0M | Research |
| 1696 Corp. | Accommodation and Food Services | $292,600 | $294,583 | 31 | $5.5M | Research |
| The Cummaquid Golf Club of Yarmouth and Barnstable | Arts, Entertainment, and Recreation | $290,808 | $293,005 | 25 | N/A | Research |
| Friedline & Carter Adjustment, LLC | Finance and Insurance | $278,267 | $280,402 | 16 | $7.0M | Research |
| Coy's Brook Inc. | Administrative and Support and Waste Management | $268,636 | $270,412 | 32 | $6.9M | Research |
| Brown Lindquist Fenuccio & Raber, INC | Professional, Scientific, and Technical Services | $252,000 | $253,393 | 16 | <$5M | Research |
| Oliver Ormon INC | Accommodation and Food Services | $248,512 | $250,051 | 50 | $8.9M | Research |
| Catalyst Architecture/interiors Inc. | Professional, Scientific, and Technical Services | $246,420 | $247,324 | 13 | <$5M | Research |
| 43 Main LLC | Accommodation and Food Services | $210,991 | $213,617 | 20 | <$5M | Research |
| Home to Stay INC | Health Care and Social Assistance | $201,372 | $203,193 | 47 | $8.1M | Research |
| A. B. Pizza Ii, Inc. | Accommodation and Food Services | $172,017 | $173,340 | 18 | <$5M | Research |
| The Sunflower School Corp | Health Care and Social Assistance | $156,390 | $158,275 | 24 | <$5M | Research |
| Seaside Gas Service Inc. | Construction | $155,188 | $156,555 | 10 | <$5M | Research |
| The Sunflower School Corp | Health Care and Social Assistance | $152,995 | $154,244 | 25 | <$5M | Research |
| Allergy & Asthma Center of Cape Cod, INC | Health Care and Social Assistance | $140,600 | $141,881 | 10 | <$5M | Research |
| Ylo, LLC | Professional, Scientific, and Technical Services | $132,300 | $133,715 | 6 | <$5M | Research |
| Cape Cod Periodontics PC | Health Care and Social Assistance | $132,122 | $133,190 | 10 | <$5M | Research |
| Massachusetts Distribution Corporation | Wholesale Trade | $129,200 | $130,898 | 7 | <$5M | Research |
| Home to Stay INC | Health Care and Social Assistance | $125,000 | $125,565 | 26 | <$5M | Research |