| Twixwood Nursery, LLC | Agriculture, Forestry, Fishing and Hunting | $1,040,900 | $1,049,459 | 142 | $14.5M | Research |
| Dockerty Health Care Services, Inc. | Health Care and Social Assistance | $922,411 | $929,303 | 62 | $10.6M | Research |
| Lake Union Conference of Sda | Other Services (except Public Administration) | $406,149 | $408,247 | 25 | <$5M | Research |
| Apple Valley Natural Foods, Inc. | Retail Trade | $352,095 | $355,549 | 24 | $6.0M | Research |
| Villwocks Outdoor Living, Inc. | Administrative and Support and Waste Management | $311,600 | $313,939 | 35 | $7.6M | Research |
| Sunnybrooke Growers | Agriculture, Forestry, Fishing and Hunting | $286,645 | $289,056 | 70 | $7.2M | Research |
| Fenner Plumbing, Inc. | Construction | $277,002 | $279,711 | 19 | $6.0M | Research |
| Adventist Frontier Missions | Other Services (except Public Administration) | $249,363 | $250,907 | 27 | $5.2M | Research |
| Berrien Dental Plc | Health Care and Social Assistance | $209,822 | $212,053 | 21 | <$5M | Research |
| Berrien Dental Plc | Health Care and Social Assistance | $209,822 | $211,334 | 23 | $5.3M | Research |
| Fenner Plumbing Inc. | Construction | $194,259 | $195,595 | 19 | $6.0M | Research |
| Pavel Staffing, LLC | Health Care and Social Assistance | $190,592 | $189,132 | 35 | $6.0M | Research |
| Life Coach Psychology, Plc | Health Care and Social Assistance | $158,192 | $159,224 | 26 | $6.1M | Research |
| Quality Air, INC | Construction | $152,112 | $153,304 | 15 | <$5M | Research |
| Eb Welding, Inc. | Other Services (except Public Administration) | $144,617 | $145,551 | 11 | <$5M | Research |
| Sunnybrooke Growers | Agriculture, Forestry, Fishing and Hunting | $139,290 | $139,908 | 30 | <$5M | Research |
| Exquisite Homes of Michigan INC | Construction | $136,855 | $137,684 | 15 | <$5M | Research |
| Exquisite Homes of Michigan, Inc. | Construction | $136,854 | $137,564 | 17 | $5.2M | Research |
| Quality Air INC | Construction | $131,965 | $132,944 | 12 | <$5M | Research |
| Asap Ministries INC | Other Services (except Public Administration) | $127,916 | $129,181 | 21 | <$5M | Research |
| Trinity Evangelical Lutheran Church of Berrien Springs, Mic | Other Services (except Public Administration) | $127,762 | $128,721 | 27 | N/A | Research |
| Zick's Specialty Meats, Inc. | Manufacturing | $125,568 | $127,259 | 17 | $6.0M | Research |
| Interlink, Inc. | Professional, Scientific, and Technical Services | $114,100 | $163,750 | 11 | <$5M | Research |
| Shembarger Asphalt Service Inc. | Construction | $112,458 | $112,889 | 12 | <$5M | Research |
| Tafcor, INC | Manufacturing | $110,500 | $111,188 | 11 | <$5M | Research |