| Kalsec, Inc. | Manufacturing | $8,484,540 | $8,582,584 | 390 | $137.6M | Research |
| Landscape Forms, Inc. | Manufacturing | $6,785,087 | $5,342,992 | 434 | $113.6M | Research |
| Workforce Strategies, Inc. | Administrative and Support and Waste Management | $5,594,200 | $5,656,358 | 500 | $78.7M | Research |
| Schupan & Sons, Inc. | Manufacturing | $5,366,607 | $5,432,278 | 500 | $122.2M | Research |
| Kalamazoo Anesthesiology, PC | Health Care and Social Assistance | $4,088,800 | $4,124,983 | 137 | $43.0M | Research |
| Stafford Smith, Inc. | Wholesale Trade | $4,026,955 | $4,077,272 | 198 | $60.7M | Research |
| B&b Trucking, Inc. | Transportation and Warehousing | $3,984,500 | $4,030,875 | 289 | $77.2M | Research |
| Mall City Mechanical, INC | Construction | $3,908,300 | $3,954,557 | 225 | $71.2M | Research |
| R. W. Lapine, Inc. | Construction | $3,835,240 | $3,879,056 | 223 | $70.6M | Research |
| Imperial Beverage Company | Wholesale Trade | $3,784,632 | $3,835,543 | 351 | $90.3M | Research |
| Kalamazoo Manufacturing Corporation Global (kmc Global) | Manufacturing | $3,757,600 | $3,800,118 | 221 | $57.9M | Research |
| Hospice Care of Southwest Michigan | Health Care and Social Assistance | $3,576,400 | $3,622,396 | 255 | N/A | Research |
| Total Plastics Resources LLC | Wholesale Trade | $3,528,800 | $3,569,773 | 43 | $11.1M | Research |
| Rx Optical Laboratories, Inc. | Manufacturing | $3,452,408 | $3,492,134 | 321 | $84.0M | Research |
| West Michigan Cancer Center | Health Care and Social Assistance | $3,213,912 | $3,253,632 | 219 | N/A | Research |
| Allied Mechanical Services, Inc. | Construction | $3,122,200 | $3,153,336 | 188 | $59.5M | Research |
| Family Health Center Inc. | Health Care and Social Assistance | $3,083,200 | $3,127,050 | 253 | N/A | Research |
| Consumers Concrete Corporation | Manufacturing | $3,052,272 | $3,087,394 | 214 | $212.3M | Research |
| Residential Opportunities Inc. | Health Care and Social Assistance | $2,842,600 | $1,357,816 | 418 | N/A | Research |
| Paragon Health, P.c. | Health Care and Social Assistance | $2,785,242 | $2,817,520 | 228 | $41.6M | Research |
| Greenleaf Hospitality, Inc. | Accommodation and Food Services | $2,654,500 | $2,688,672 | 318 | $99.4M | Research |
| The Csm Group, Inc. | Construction | $2,534,545 | $2,561,488 | 137 | $156.1M | Research |
| Midwest Fastener Corp. | Wholesale Trade | $2,450,310 | $2,478,659 | 303 | $92.8M | Research |
| Continental Linen Services, Inc. | Other Services (except Public Administration) | $2,386,280 | $2,413,935 | 221 | $42.2M | Research |
| Arvco Container Corporation | Manufacturing | $2,303,891 | $2,332,804 | 187 | $185.5M | Research |