| Mckenzie Memorial Hospital | Health Care and Social Assistance | $2,503,508 | $2,533,207 | 167 | N/A |  Research |
| Tri County Equipment, Inc. | Wholesale Trade | $1,706,348 | $1,722,188 | 170 | $52.1M | Research |
| Jensen Bridge & Supply Company | Manufacturing | $1,177,243 | $1,185,435 | 91 | $22.2M | Research |
| Tds Pharmacy, INC | Real Estate and Rental and Leasing | $1,167,100 | $1,176,533 | 151 | $68.2M | Research |
| Tubbs Brothers, Inc. | Retail Trade | $725,683 | $730,313 | 59 | $14.9M | Research |
| Tmc Marketing Inc. | Retail Trade | $573,562 | $578,700 | 49 | $11.5M | Research |
| Tnt Equipment INC | Wholesale Trade | $458,129 | $460,551 | 31 | $9.5M | Research |
| Tnt Equipment, INC | Wholesale Trade | $458,128 | $460,558 | 31 | $9.5M | Research |
| Production Development Systems, LLC | Manufacturing | $365,888 | $369,847 | 23 | $6.0M | Research |
| Production Development Systems LLC | Manufacturing | $365,888 | $368,734 | 25 | $6.1M | Research |
| Deckerville Veterinary Clinic PC | Professional, Scientific, and Technical Services | $361,800 | $366,453 | 29 | <$5M | Research |
| Dickendesher INC | Accommodation and Food Services | $355,808 | $359,678 | 110 | $19.5M | Research |
| Graff Chevrolet, Buick, INC | Retail Trade | $342,542 | $346,020 | 43 | $10.8M | Research |
| Nelson Weaver | Agriculture, Forestry, Fishing and Hunting | $150,200 | $151,051 | 47 | $7.7M | Research |
| Stoutenburg Inc. | Manufacturing | $148,998 | $150,337 | 23 | $22.8M | Research |
| Stoutenburg Inc. | Manufacturing | $148,998 | $149,888 | 23 | $22.8M | Research |
| Sandusky Motors, Inc. | Retail Trade | $128,922 | $0 | 14 | <$5M | Research |
| Moore Sanilac Restaurant LLC | Accommodation and Food Services | $128,184 | $128,893 | 22 | <$5M | Research |
| Sandusky Motors, INC | Wholesale Trade | $127,017 | $128,449 | 14 | <$5M | Research |
| Sandusky Motors Inc. | Wholesale Trade | $127,017 | $128,752 | 14 | <$5M | Research |
| Wadsworth Farms, Inc. | Agriculture, Forestry, Fishing and Hunting | $126,900 | $127,679 | 20 | <$5M | Research |
| Kursinsky Family Enterprises, Inc. | Accommodation and Food Services | $116,300 | $117,382 | 38 | $6.7M | Research |
| Sanilac Smiles Dental Care, Pllc | Health Care and Social Assistance | $115,062 | $116,556 | 11 | <$5M | Research |
| Rm Deliveries INC | Transportation and Warehousing | $110,800 | $111,874 | 15 | <$5M | Research |
| Stoutenburg Farms, LLC | Agriculture, Forestry, Fishing and Hunting | $101,084 | $102,058 | 7 | <$5M | Research |