| Riverview Healthcare Association | Health Care and Social Assistance | $5,836,300 | $5,903,617 | 389 | N/A |  Research |
| Widseth Smith Nolting & Associates, Inc. | Professional, Scientific, and Technical Services | $3,250,000 | $3,287,753 | 200 | $24.7M | Research |
| Northwestern Mental Health Center, Inc. | Health Care and Social Assistance | $1,760,700 | $1,777,921 | 153 | N/A | Research |
| Dee INC | Manufacturing | $816,262 | $819,981 | 66 | $17.3M | Research |
| Dee, Inc. | Manufacturing | $816,200 | $822,798 | 86 | $22.5M | Research |
| Agricultural Utilization Research Institute, Inc. | Professional, Scientific, and Technical Services | $483,700 | $486,271 | 30 | N/A | Research |
| Eickhof Columbaria, INC | Manufacturing | $370,600 | $374,276 | 36 | $10.1M | Research |
| Minnesota Northern R I | Transportation and Warehousing | $321,900 | $324,520 | 27 | $6.8M | Research |
| Eickhof Columbaria INC | Wholesale Trade | $305,210 | $307,443 | 25 | $7.7M | Research |
| Northern Lights Fiber Optic Splicing Inc. | Construction | $235,842 | $236,805 | 12 | <$5M | Research |
| Diocese of Crookston | Other Services (except Public Administration) | $216,700 | $218,000 | 19 | N/A | Research |
| Polk County Developmental Achievement Center, Inc. | Health Care and Social Assistance | $212,700 | $213,947 | 24 | N/A | Research |
| H N Quality Plumbing, Inc. | Construction | $186,800 | $187,803 | 17 | $5.4M | Research |
| Polk County Developmental Achievement Center Inc. | Health Care and Social Assistance | $173,667 | $174,443 | 59 | N/A | Research |
| Crookston Building Center, Inc. | Retail Trade | $169,400 | $170,686 | 13 | <$5M | Research |
| Crookston Welding Machine Co. | Other Services (except Public Administration) | $154,100 | $155,278 | 16 | <$5M | Research |
| Majek, LLC | Accommodation and Food Services | $149,612 | $151,054 | 49 | $8.7M | Research |
| Jaclyn M Jensen DDS PC | Health Care and Social Assistance | $147,700 | $148,809 | 14 | <$5M | Research |
| Crookston Fuel Company | Retail Trade | $147,700 | $148,566 | 23 | $5.5M | Research |
| Crookston Valley Cooperative, INC | Wholesale Trade | $146,553 | $147,680 | 6 | <$5M | Research |
| Northern Lights Fiber Optic Splicing, Inc. | Construction | $145,807 | $146,715 | 11 | <$5M | Research |
| Longtin Agency INC | Finance and Insurance | $145,600 | $33,795 | 6 | <$5M | Research |
| Best Used Trucks of Mn | Retail Trade | $142,600 | $143,694 | 12 | <$5M | Research |
| Brost Chevrolet Inc. | Retail Trade | $141,950 | $142,343 | 13 | <$5M | Research |
| Christian Brothers Ford, INC | Retail Trade | $141,260 | $145,213 | 14 | <$5M | Research |