| Le Sueur Incorporated | Manufacturing | $4,540,028 | $3,998,618 | 348 | $91.1M |  Research |
| The Canopy Group | Finance and Insurance | $378,780 | $381,022 | 33 | $17.0M | Research |
| Seaver Company | Wholesale Trade | $337,500 | $324,052 | 41 | $10.6M | Research |
| Technipac, Inc. | Manufacturing | $321,270 | $323,735 | 39 | $38.7M | Research |
| Scott's Helicoptor Services INC | Agriculture, Forestry, Fishing and Hunting | $310,660 | $312,610 | 16 | <$5M | Research |
| Scott's Helicopter Services INC | Transportation and Warehousing | $267,610 | $360,771 | 34 | $8.6M | Research |
| Oak Terrace Senior Housing of Lesueur, LLC | Health Care and Social Assistance | $260,700 | $262,959 | 33 | $5.6M | Research |
| L S Engineers Inc. | Professional, Scientific, and Technical Services | $251,945 | $253,319 | 17 | <$5M | Research |
| Del's Construction Company, Inc. | Construction | $217,670 | $219,304 | 24 | $27.3M | Research |
| Aero Transport Incorporated | Transportation and Warehousing | $197,000 | $198,184 | 37 | $7.5M | Research |
| Dj Siehndel Construction | Construction | $172,519 | $173,818 | 9 | <$5M | Research |
| Syneco Systems INC | Manufacturing | $170,000 | $170,859 | 10 | <$5M | Research |
| Radermacher Foods of Le Sueur, Inc. | Retail Trade | $156,707 | $158,068 | 14 | <$5M | Research |
| Julianne Siehndel | Construction | $123,820 | $124,408 | 9 | <$5M | Research |
| Minnesota Valley Veterinary Services, Pllc | Professional, Scientific, and Technical Services | $122,070 | $122,748 | 18 | <$5M | Research |
| Nuessmeier Electric Inc. | Construction | $121,660 | $122,407 | 10 | <$5M | Research |
| Church of St. Anne | Other Services (except Public Administration) | $119,100 | $119,926 | 18 | N/A | Research |
| Don Distel Grain Systems, Inc. | Construction | $110,100 | $110,782 | 13 | $14.8M | Research |
| Lesueur Family Dental, Pllc | Health Care and Social Assistance | $99,627 | $100,391 | 6 | <$5M | Research |
| Le Sueur Family Dental Pllc | Health Care and Social Assistance | $86,805 | $87,538 | 6 | <$5M | Research |
| Valley Lanes INC | Accommodation and Food Services | $84,000 | $84,443 | 22 | <$5M | Research |
| Oberle, Tully & Company | Professional, Scientific, and Technical Services | $79,075 | $79,649 | 5 | <$5M | Research |
| Johnson Aggregates | Mining, Quarrying, and Oil and Gas Extraction | $76,772 | $77,412 | 11 | <$5M | Research |
| Schoeppner & Associates, PA | Professional, Scientific, and Technical Services | $71,940 | $90,445 | 7 | <$5M | Research |
| Anderson & Skubitz Pllc | Professional, Scientific, and Technical Services | $70,000 | $70,354 | 6 | <$5M | Research |