| Dan B Murphy's Restaurant & Bar, LLC | Accommodation and Food Services | $71,396 | $72,205 | 45 | $8.0M |  Research |
| Mayley's Pest Control, LLC | Administrative and Support and Waste Management | $65,600 | $66,087 | 10 | <$5M | Research |
| Bayou Caddy Fisheries, Inc. | Wholesale Trade | $65,100 | $65,931 | 4 | <$5M | Research |
| Santa Cruz Insurance Group, LLC | Finance and Insurance | $64,400 | $64,903 | 5 | <$5M | Research |
| Newman Eye Clinic, PA | Health Care and Social Assistance | $63,138 | $63,609 | 5 | <$5M | Research |
| Santa Cruz Insurance Group LLC | Finance and Insurance | $62,965 | $63,364 | 4 | <$5M | Research |
| James J. Chiniche, PA INC | Professional, Scientific, and Technical Services | $62,848 | $63,623 | 11 | <$5M | Research |
| Pet Haven Veterinary Hospital LLC | Professional, Scientific, and Technical Services | $62,112 | $62,690 | 8 | <$5M | Research |
| Avocados of Ms, LLC | Accommodation and Food Services | $58,100 | $58,599 | 17 | <$5M | Research |
| Accelerated Physical Therapy & Occupational Health INC | Health Care and Social Assistance | $56,551 | $56,771 | 6 | <$5M | Research |
| Accelerated Physical Therapy & Occupational Health INC | Health Care and Social Assistance | $56,550 | $57,070 | 6 | <$5M | Research |
| Town Pharmacy and Gifts LLC | Retail Trade | $56,500 | $56,958 | 8 | <$5M | Research |
| Loumis Air LLC | Construction | $56,500 | $57,049 | 8 | <$5M | Research |
| Barnes Mayfield Corp | Professional, Scientific, and Technical Services | $55,300 | $21,087 | 11 | <$5M | Research |
| Bay St Louis Newspapers INC | Information | $55,000 | $55,556 | 9 | <$5M | Research |
| James C Crittendon, M.d. | Health Care and Social Assistance | $54,034 | $54,693 | 8 | <$5M | Research |
| S & L Maritime Consulting LLC | Professional, Scientific, and Technical Services | $50,687 | $51,219 | 5 | <$5M | Research |
| Lrn Properties LLC | Accommodation and Food Services | $50,172 | $50,439 | 7 | <$5M | Research |
| Mockingbird Cafe LLC | Accommodation and Food Services | $49,442 | $49,716 | 10 | <$5M | Research |
| Mockingbird Cafe LLC | Accommodation and Food Services | $49,406 | $49,585 | 11 | <$5M | Research |
| Best Corporation Inc. | Finance and Insurance | $49,207 | $49,520 | 7 | <$5M | Research |
| Do-Mar, LLC | Construction | $48,700 | $49,405 | 7 | <$5M | Research |
| Hadden Investments INC | Finance and Insurance | $48,644 | $49,005 | 3 | <$5M | Research |
| The Sycamore House LLC | Accommodation and Food Services | $47,937 | $48,605 | 12 | <$5M | Research |
| Gardner & Cruthirds INC | Accommodation and Food Services | $46,228 | $46,568 | 10 | <$5M | Research |