| North Sunflower County Educational Foundation | Educational Services | $119,228 | $120,293 | 27 | N/A |  Research |
| Professional Lawn Sprinklers INC | Professional, Scientific, and Technical Services | $115,620 | $116,511 | 6 | <$5M | Research |
| Edward D Mccain Jr. Et Al | Agriculture, Forestry, Fishing and Hunting | $64,134 | $64,392 | 31 | <$5M | Research |
| Mccain Planting Partnership | Agriculture, Forestry, Fishing and Hunting | $62,500 | $62,752 | 3 | <$5M | Research |
| Edward D Mccain Jr Et Al | Agriculture, Forestry, Fishing and Hunting | $58,600 | $58,950 | 28 | <$5M | Research |
| Griffin Trucking, INC | Transportation and Warehousing | $54,935 | $55,283 | 11 | <$5M | Research |
| Griffin Trucking, INC | Transportation and Warehousing | $54,809 | $55,074 | 10 | <$5M | Research |
| One Way Construction | Construction | $54,196 | $54,546 | 4 | <$5M | Research |
| Professional Lawn Sprinklers, INC | Other Services (except Public Administration) | $50,000 | $50,340 | 6 | <$5M | Research |
| Ruleville-Drew Grain Elevator Company, Inc. | Wholesale Trade | $36,829 | $37,035 | 11 | <$5M | Research |
| Ruleville Drew Grain Elevator INC | Transportation and Warehousing | $36,829 | $37,003 | 9 | <$5M | Research |
| Sunflower Construction LLC | Construction | $33,210 | $33,290 | 3 | <$5M | Research |
| Sunflower Construction LLC | Construction | $33,210 | $33,667 | 3 | <$5M | Research |
| Robert Lawson Holladay, Sr. | Professional, Scientific, and Technical Services | $32,215 | $32,446 | 1 | <$5M | Research |
| Stephen C Hausner Farm | Agriculture, Forestry, Fishing and Hunting | $30,400 | $30,704 | 6 | <$5M | Research |
| Wesley Chandler | Agriculture, Forestry, Fishing and Hunting | $29,800 | $29,913 | 1 | <$5M | Research |
| North Drew Freight, Inc. | Transportation and Warehousing | $29,511 | $29,680 | 2 | <$5M | Research |
| North Drew Freight, Inc. | Transportation and Warehousing | $29,511 | $29,710 | 2 | <$5M | Research |
| Super 2 LLC | Retail Trade | $27,270 | $27,659 | 4 | <$5M | Research |
| Mccain Planting Partnership | Agriculture, Forestry, Fishing and Hunting | $26,900 | $27,046 | 2 | <$5M | Research |
| Main Street Deli and Gifts LLC | Accommodation and Food Services | $24,575 | $10,417 | 3 | <$5M | Research |
| Delta Sky LLC | Agriculture, Forestry, Fishing and Hunting | $24,200 | $24,265 | 1 | <$5M | Research |
| Andrews Dental Clinic, P.a. | Health Care and Social Assistance | $21,100 | $21,249 | 3 | <$5M | Research |
| Howard Williams | Agriculture, Forestry, Fishing and Hunting | $20,833 | $20,881 | 1 | <$5M | Research |
| Warren Lee Childs | Agriculture, Forestry, Fishing and Hunting | $20,833 | $20,893 | 1 | <$5M | Research |