| South Sunflower County Hospital | Health Care and Social Assistance | $2,144,200 | $2,172,574 | 222 | N/A |  Research |
| Gresham Petroleum Company | Utilities | $1,164,000 | $1,178,223 | 89 | N/A | Research |
| Gresham Petroleum Company | Wholesale Trade | $1,164,000 | $1,171,399 | 89 | $22.9M | Research |
| Sunflower Humphreys Counties Progress, INC | Health Care and Social Assistance | $583,909 | $582,753 | 59 | N/A | Research |
| Sunflower Humphreys Counties Progress | Health Care and Social Assistance | $583,909 | $587,220 | 59 | N/A | Research |
| Irrigation Equipment INC | Construction | $427,870 | $430,266 | 38 | $11.8M | Research |
| Indianola Educational Foundation, Inc. | Educational Services | $348,200 | $350,242 | 48 | $5.8M | Research |
| Indianola Pecan House, Inc. | Wholesale Trade | $325,500 | $328,393 | 132 | $34.0M | Research |
| Indianola Pecan House INC | Wholesale Trade | $325,500 | $328,023 | 30 | $7.7M | Research |
| Indi-Bell INC | Manufacturing | $323,000 | $325,248 | 37 | $13.1M | Research |
| Indi-Bel Inc. | Manufacturing | $280,908 | $282,355 | 34 | $12.0M | Research |
| Gardner Engineering P.a. | Professional, Scientific, and Technical Services | $211,800 | $213,686 | 23 | <$5M | Research |
| Selecta Motors, INC | Retail Trade | $209,200 | $210,828 | 18 | <$5M | Research |
| Indianola Eye Clinic | Health Care and Social Assistance | $199,370 | $200,370 | 26 | $6.1M | Research |
| Indianola Eye Clinic, PA | Health Care and Social Assistance | $197,100 | $201,195 | 26 | $6.1M | Research |
| Indianola Foods, INC | Retail Trade | $193,402 | $194,139 | 48 | $12.0M | Research |
| Irrigation Fittings, INC | Manufacturing | $172,620 | $173,612 | 17 | $16.9M | Research |
| Irrigation Fittings, INC | Manufacturing | $172,620 | $173,296 | 19 | $18.8M | Research |
| Delta Western Construction Ii, Inc. | Other Services (except Public Administration) | $166,700 | $168,632 | 20 | <$5M | Research |
| Nexion Health at Indianola, Inc. | Health Care and Social Assistance | $166,503 | $168,330 | 81 | $13.8M | Research |
| Mid Delta Metal & Southern Agri Systems & Construction, INC | Manufacturing | $153,700 | $154,584 | 20 | <$5M | Research |
| Mid Delta Metal & Southern Agri Systems & Construction, INC | Manufacturing | $153,700 | $154,576 | 21 | $5.1M | Research |
| Feed Haulers Ii, Inc. | Transportation and Warehousing | $153,300 | $154,283 | 16 | <$5M | Research |
| Giachelli Pr LLC | Professional, Scientific, and Technical Services | $150,275 | $0 | 3 | <$5M | Research |
| Holly Ridge Planting Co | Agriculture, Forestry, Fishing and Hunting | $144,480 | $145,228 | 30 | <$5M | Research |