| Winston County Medical Foundation | Health Care and Social Assistance | $2,463,500 | $2,491,283 | 384 | N/A |  Research |
| Hardwire, Inc. | Manufacturing | $551,808 | $557,847 | 77 | $20.2M | Research |
| Rives & Reynolds Lumber Co Inc. | Manufacturing | $396,038 | $399,109 | 40 | $39.7M | Research |
| Smyth Lake Company INC | Accommodation and Food Services | $378,434 | $380,452 | 43 | $13.4M | Research |
| The Fair Companies INC | Retail Trade | $329,988 | $331,977 | 48 | $16.1M | Research |
| The Fair Companies INC | Retail Trade | $326,100 | $329,243 | 52 | $17.4M | Research |
| Rives & Reynolds Lumber Co, Inc. | Manufacturing | $304,560 | $306,277 | 23 | $22.8M | Research |
| Briye LLC | Professional, Scientific, and Technical Services | $289,873 | $291,394 | 14 | <$5M | Research |
| Briye, LLC | Professional, Scientific, and Technical Services | $289,800 | $292,593 | 17 | <$5M | Research |
| Bullock Auto Group, Inc. | Retail Trade | $284,200 | $286,213 | 26 | $6.6M | Research |
| Fair Propane Gas Systems Inc. | Retail Trade | $279,400 | $281,402 | 31 | $7.4M | Research |
| Smyth Lake Company Inc. | Accommodation and Food Services | $270,300 | $273,041 | 48 | $15.0M | Research |
| Crowson-Thornton LLC | Retail Trade | $245,100 | $247,013 | 30 | $7.6M | Research |
| Louisville Winston Education Foundation INC | Educational Services | $228,200 | $229,557 | 32 | N/A | Research |
| Louisville Winston Education Foundation, INC | Educational Services | $224,500 | $226,179 | 32 | N/A | Research |
| Forming Agrotors INC | Agriculture, Forestry, Fishing and Hunting | $223,968 | $225,255 | 19 | <$5M | Research |
| Forming Agrotors INC | Agriculture, Forestry, Fishing and Hunting | $223,968 | $226,404 | 19 | <$5M | Research |
| US Applicators, LLC | Agriculture, Forestry, Fishing and Hunting | $220,700 | $221,782 | 20 | <$5M | Research |
| Hughes Management INC | Professional, Scientific, and Technical Services | $216,800 | $218,715 | 19 | <$5M | Research |
| Baker's Ready Mix & Construction LLC | Manufacturing | $191,113 | $192,971 | 27 | $26.8M | Research |
| Ctc, Inc. | Transportation and Warehousing | $185,083 | $187,339 | 25 | <$5M | Research |
| Hughes Construction Company, Inc. | Construction | $181,900 | $183,410 | 15 | <$5M | Research |
| Winston Building and Supply Company | Retail Trade | $178,100 | $179,406 | 22 | <$5M | Research |
| Louisville Dental Associates, Llc. | Health Care and Social Assistance | $150,000 | $151,985 | 8 | <$5M | Research |
| Moody Construction Company INC | Real Estate and Rental and Leasing | $148,100 | $149,684 | 11 | <$5M | Research |