| Neshoba County General Hospital | Health Care and Social Assistance | $4,817,110 | $4,854,591 | 471 | N/A |  Research |
| Mclain Plumbing and Electrical Services | Construction | $1,159,065 | $1,077,737 | 114 | $36.1M | Research |
| B & G Equipment, INC | Real Estate and Rental and Leasing | $1,012,379 | $1,018,010 | 65 | $29.4M | Research |
| Junction Management, LLC | Retail Trade | $681,300 | $689,741 | 175 | $43.7M | Research |
| Performance Therapy, LLC | Health Care and Social Assistance | $505,580 | $508,529 | 38 | $10.3M | Research |
| Marshall Ford Co, Inc. | Retail Trade | $462,100 | $465,065 | 43 | $10.8M | Research |
| Thomasson Lumber Company | Manufacturing | $420,900 | $423,355 | 36 | $35.7M | Research |
| Williams Brothers INC | Retail Trade | $391,000 | $394,725 | 64 | $21.4M | Research |
| Quality Hospice Care, INC | Health Care and Social Assistance | $390,122 | $392,901 | 31 | $5.3M | Research |
| Windham Tractor and Implement Co. | Retail Trade | $387,475 | $389,587 | 32 | $6.6M | Research |
| Prince Oil Company INC | Wholesale Trade | $342,334 | $346,732 | 31 | $8.0M | Research |
| Prince Oil Company, Inc. | Wholesale Trade | $342,300 | $346,247 | 33 | $8.5M | Research |
| Richard Sisson Trucking INC | Transportation and Warehousing | $337,500 | $341,138 | 47 | $11.9M | Research |
| B & G Transport, LLC | Transportation and Warehousing | $311,444 | $313,210 | 55 | $14.7M | Research |
| Plantation Thinning Specialist LLC | Agriculture, Forestry, Fishing and Hunting | $300,992 | $303,466 | 31 | <$5M | Research |
| Plantation Thinning Specialist LLC | Agriculture, Forestry, Fishing and Hunting | $297,885 | $299,868 | 32 | <$5M | Research |
| Griffis Motors, INC | Retail Trade | $267,400 | $269,216 | 25 | $6.3M | Research |
| D&w Tire and Muffler Company, INC | Other Services (except Public Administration) | $264,467 | $267,010 | 29 | $5.7M | Research |
| Conn Enterprises Incorporated | Retail Trade | $261,600 | $265,008 | 36 | $5.6M | Research |
| Taxx Revolution INC | Finance and Insurance | $252,860 | $0 | 19 | $9.8M | Research |
| B&g Wood INC | Agriculture, Forestry, Fishing and Hunting | $250,438 | $252,743 | 23 | <$5M | Research |
| Philadelphia Energy Transport Co. | Transportation and Warehousing | $247,800 | $250,863 | 19 | <$5M | Research |
| Nhc Distributors, Inc. | Wholesale Trade | $236,668 | $238,509 | 27 | $8.3M | Research |
| B & G Wood, INC | Agriculture, Forestry, Fishing and Hunting | $234,426 | $235,756 | 25 | <$5M | Research |
| Tim Breland Logging, INC | Agriculture, Forestry, Fishing and Hunting | $233,500 | $235,744 | 26 | <$5M | Research |