| Tippah County Hospital | Health Care and Social Assistance | $1,788,914 | $1,802,728 | 243 | N/A | Research |
| Hankins, INC | Manufacturing | $1,694,800 | $1,705,062 | 110 | $109.1M | Research |
| Synergy Home Furnishings LLC | Manufacturing | $643,900 | $652,421 | 25 | $6.5M | Research |
| Tippah Electric Power Association | Utilities | $616,200 | $620,505 | 43 | N/A | Research |
| Elite Elastomers, Inc. | Manufacturing | $494,900 | $498,574 | 55 | $54.6M | Research |
| Wg Construction Company Inc. | Construction | $458,558 | $460,920 | 37 | $11.5M | Research |
| Wg Construction Company, Inc. | Construction | $446,700 | $452,183 | 14 | <$5M | Research |
| Dees Oil Company INC | Wholesale Trade | $430,400 | $434,238 | 35 | $9.0M | Research |
| Ceca, LLC | Manufacturing | $328,300 | $332,285 | 32 | $7.8M | Research |
| Ceca LLC | Manufacturing | $265,120 | $266,841 | 37 | $9.0M | Research |
| Roberts Builders INC | Construction | $241,118 | $243,040 | 20 | $22.8M | Research |
| Primary Care Clinic of Ripley, PA | Health Care and Social Assistance | $238,400 | $240,294 | 23 | $7.2M | Research |
| Butch Davis Chevrolet, Inc. | Retail Trade | $225,500 | $227,172 | 18 | <$5M | Research |
| Hankins Forest Products, Inc. | Agriculture, Forestry, Fishing and Hunting | $212,700 | $214,029 | 15 | <$5M | Research |
| Eaton, Babb, & Smith, PA | Professional, Scientific, and Technical Services | $208,700 | $209,769 | 17 | $5.4M | Research |
| Rebel Services LLC | Other Services (except Public Administration) | $204,000 | $205,688 | 17 | <$5M | Research |
| Sullivan Surveying, Inc. | Professional, Scientific, and Technical Services | $202,700 | $204,138 | 23 | <$5M | Research |
| Roberts Builders, INC | Construction | $194,203 | $195,654 | 19 | $21.6M | Research |
| Rebel Services, LLC | Transportation and Warehousing | $170,600 | $172,582 | 17 | <$5M | Research |
| Clemmer Construction Company LLC | Construction | $166,800 | $168,171 | 18 | $5.7M | Research |
| Nursemed,llc | Health Care and Social Assistance | $156,200 | $157,089 | 25 | <$5M | Research |
| Family Care Clinic of Ripley | Health Care and Social Assistance | $155,100 | $156,315 | 18 | $5.6M | Research |
| Farrow Ward Ford INC | Retail Trade | $151,000 | $152,378 | 16 | <$5M | Research |
| Lindsey, Davis, and Associates Cpas, PA | Professional, Scientific, and Technical Services | $146,600 | $147,684 | 11 | <$5M | Research |
| Gatekeeper Enterprises, INC | Accommodation and Food Services | $146,100 | $147,673 | 18 | <$5M | Research |