| Sharkey Issaquena Community Hospital | Health Care and Social Assistance | $1,375,000 | $1,394,403 | 142 | N/A |  Research |
| Sharkey Issaquena Community Hospital | Health Care and Social Assistance | $1,271,217 | $1,284,847 | 120 | N/A | Research |
| Mississippi Christian Family Services Inc. | Health Care and Social Assistance | $207,938 | $209,197 | 64 | N/A | Research |
| Mississippi Christian Family Services, Inc. | Health Care and Social Assistance | $202,600 | $204,238 | 47 | N/A | Research |
| Sharkey Issaquena Academy Foundation | Educational Services | $127,721 | $128,374 | 26 | N/A | Research |
| Sharkey-Issaquena Academy | Educational Services | $127,700 | $129,073 | 38 | N/A | Research |
| B.l. Lamensdorf Farms | Agriculture, Forestry, Fishing and Hunting | $107,000 | $107,874 | 30 | <$5M | Research |
| Service Lumber Company, Inc. | Retail Trade | $92,100 | $92,622 | 11 | <$5M | Research |
| Sunflower, No. 88, Inc. | Retail Trade | $90,200 | $90,783 | 22 | $5.5M | Research |
| Grundfest & Klaus Inc. | Agriculture, Forestry, Fishing and Hunting | $76,400 | $76,729 | 19 | <$5M | Research |
| Carter Plantation Limited | Agriculture, Forestry, Fishing and Hunting | $69,491 | $70,076 | 7 | <$5M | Research |
| Carter Plantation Limited | Agriculture, Forestry, Fishing and Hunting | $69,400 | $69,926 | 7 | <$5M | Research |
| Kelso Farms | Agriculture, Forestry, Fishing and Hunting | $64,865 | $23,293 | 3 | <$5M | Research |
| Deer Creek Pharmacy, LLC | Retail Trade | $62,700 | $63,113 | 15 | <$5M | Research |
| Marty Long | Accommodation and Food Services | $58,304 | $58,592 | 7 | <$5M | Research |
| Bryant Group of Ms, Inc. | Professional, Scientific, and Technical Services | $57,800 | $58,137 | 7 | <$5M | Research |
| Bryant Group of Ms, Inc. | Professional, Scientific, and Technical Services | $56,800 | $57,220 | 8 | <$5M | Research |
| Rolling Fork Medical Clinic LLC | Health Care and Social Assistance | $56,400 | $56,980 | 6 | <$5M | Research |
| Ms Breast Foundation | Public Administration | $56,100 | $56,538 | 14 | N/A | Research |
| O.j. Sharpe Jr. Farms | Agriculture, Forestry, Fishing and Hunting | $53,928 | $54,228 | 3 | <$5M | Research |
| Holly Grove Partnership | Agriculture, Forestry, Fishing and Hunting | $51,140 | $51,336 | 3 | <$5M | Research |
| G M Farms | Agriculture, Forestry, Fishing and Hunting | $46,900 | $47,231 | 8 | <$5M | Research |
| Lynndale Partners | Agriculture, Forestry, Fishing and Hunting | $45,731 | $45,995 | 4 | <$5M | Research |
| Carter Brothers Farms Inc. | Agriculture, Forestry, Fishing and Hunting | $44,849 | $45,226 | 7 | <$5M | Research |
| Carter Brothers Farm, Inc. | Agriculture, Forestry, Fishing and Hunting | $44,800 | $45,140 | 7 | <$5M | Research |