| North Sunflower Medical Center | Health Care and Social Assistance | $4,300,000 | $4,342,882 | 500 | N/A | Research |
| Woodard Eubanks & Sons, LLP | Transportation and Warehousing | $354,200 | $357,985 | 38 | $5.7M | Research |
| Ruleville Manufacturing Company, Inc. | Manufacturing | $266,950 | $269,005 | 82 | $28.9M | Research |
| Precision Delta Corporation | Manufacturing | $218,600 | $219,971 | 21 | $5.1M | Research |
| Turner Inflatables | Transportation and Warehousing | $125,000 | $125,660 | 6 | <$5M | Research |
| Bills Body Shop, Inc. | Other Services (except Public Administration) | $111,325 | $111,978 | 8 | <$5M | Research |
| Veronica James | Retail Trade | $103,158 | $104,441 | 11 | <$5M | Research |
| Arant Farms | Agriculture, Forestry, Fishing and Hunting | $56,060 | $56,528 | 3 | <$5M | Research |
| Archibald's Antique Restoration & Body Repair, LLC | Other Services (except Public Administration) | $53,560 | $53,981 | 5 | <$5M | Research |
| Carver Brothers Partnership | Agriculture, Forestry, Fishing and Hunting | $49,500 | $49,774 | 2 | <$5M | Research |
| Carver Brothers Partnership | Agriculture, Forestry, Fishing and Hunting | $49,500 | $49,957 | 2 | <$5M | Research |
| Levester Moton | Construction | $39,936 | $40,152 | 4 | <$5M | Research |
| 3 County Farms | Agriculture, Forestry, Fishing and Hunting | $37,354 | $37,837 | 11 | <$5M | Research |
| Clark Planting Partnership | Agriculture, Forestry, Fishing and Hunting | $37,200 | $35,962 | 5 | <$5M | Research |
| 3 County Farms Partnership | Agriculture, Forestry, Fishing and Hunting | $36,100 | $36,496 | 5 | <$5M | Research |
| Grittman Farms Partnership II | Agriculture, Forestry, Fishing and Hunting | $35,700 | $56,941 | 4 | <$5M | Research |
| Clark Planting Partnership | Agriculture, Forestry, Fishing and Hunting | $35,570 | $36,026 | 5 | <$5M | Research |
| Mississippi Police Supply Company INC | Retail Trade | $26,700 | $26,812 | 5 | <$5M | Research |
| Mississippi Police Company, INC | Retail Trade | $26,700 | $26,852 | 5 | <$5M | Research |
| Okema White | Health Care and Social Assistance | $26,688 | $26,763 | 8 | <$5M | Research |
| Lindy's Trucking LLC | Transportation and Warehousing | $26,580 | $26,646 | 2 | <$5M | Research |
| Woods Insurance Brokerage and Tax Services | Professional, Scientific, and Technical Services | $26,276 | $26,456 | 6 | <$5M | Research |
| Woods Insurance Brokerage and Tax Services | Professional, Scientific, and Technical Services | $26,276 | $26,424 | 6 | <$5M | Research |
| Lovett Auto & Tractor Parts, Inc. | Retail Trade | $24,872 | $25,018 | 6 | <$5M | Research |
| Haney Farming Partnership | Agriculture, Forestry, Fishing and Hunting | $23,203 | $23,329 | 5 | <$5M | Research |