| Mississippi Methodist Senior Services in | Health Care and Social Assistance | $7,035,775 | $7,116,296 | 499 | $84.9M |  Research |
| Wise Staffing Services, Inc. | Administrative and Support and Waste Management | $5,931,285 | $6,011,073 | 500 | $78.7M | Research |
| Labor Source, L.l.c. | Administrative and Support and Waste Management | $4,699,303 | $4,762,389 | 500 | $78.7M | Research |
| Live Mobile, LLC | Information | $3,473,300 | $3,522,687 | 483 | $81.1M | Research |
| Maloney Management, LLC | Construction | $2,770,800 | $2,804,961 | 229 | $260.9M | Research |
| Cardiology Associates of North Mississippi | Health Care and Social Assistance | $2,161,800 | $2,185,039 | 203 | $47.0M | Research |
| Wise Medical Staffing, Inc. | Administrative and Support and Waste Management | $2,038,313 | $2,064,726 | 492 | $77.4M | Research |
| Central Service Association | Professional, Scientific, and Technical Services | $1,988,200 | $2,010,567 | 139 | $28.7M | Research |
| Tombigbee Electric Power Association | Public Administration | $1,950,000 | $1,970,746 | 134 | N/A | Research |
| Independent Furniture Supply Co., Inc. | Manufacturing | $1,893,537 | $1,908,218 | 278 | $275.7M | Research |
| Journal, Inc. | Information | $1,844,700 | $1,855,516 | 217 | $36.4M | Research |
| Journal, Inc. | Information | $1,844,692 | $1,861,168 | 178 | $29.9M | Research |
| Day-Help, L.l.c. | Administrative and Support and Waste Management | $1,838,823 | $1,863,609 | 273 | $43.0M | Research |
| Onesource Staffing, L.l.c. | Administrative and Support and Waste Management | $1,644,813 | $1,665,587 | 351 | $55.2M | Research |
| Epsco, Inc. | Administrative and Support and Waste Management | $1,467,400 | $1,486,657 | 245 | $38.6M | Research |
| American Family Association, Inc. | Other Services (except Public Administration) | $1,390,855 | $1,403,374 | 124 | N/A | Research |
| Family Resource Center of North Mississippi | Health Care and Social Assistance | $1,299,792 | $1,311,365 | 99 | N/A | Research |
| The Family Resource Center of North Mississippi, Inc. | Health Care and Social Assistance | $1,242,303 | $1,258,164 | 99 | N/A | Research |
| Barnes Crossing Auto LLC | Retail Trade | $1,175,700 | $1,185,106 | 106 | $26.7M | Research |
| B & B Concrete INC | Manufacturing | $1,130,000 | $1,143,065 | 107 | $29.9M | Research |
| Gibson Corrugated, LLC | Manufacturing | $1,124,500 | $1,133,246 | 104 | $103.2M | Research |
| Digestive Health Specialsts PA | Health Care and Social Assistance | $1,011,100 | $1,018,880 | 64 | $20.1M | Research |
| Mitchell, Mcnutt & Sams, P.a. | Professional, Scientific, and Technical Services | $1,004,600 | $1,010,544 | 68 | $16.5M | Research |
| Celebrity Coaches LLC | Transportation and Warehousing | $1,003,690 | $1,015,177 | 60 | $23.1M | Research |
| Franklin Collection Services, Inc. | Administrative and Support and Waste Management | $909,800 | $915,992 | 110 | $20.8M | Research |