| Dimco, Inc. | Professional, Scientific, and Technical Services | $210,758 | $212,161 | 21 | <$5M | Research |
| Cannon Import of Vicksburg, LLC | Retail Trade | $210,700 | $211,993 | 17 | <$5M | Research |
| Junius Ward Johnson Ymca | Arts, Entertainment, and Recreation | $206,800 | $208,908 | 78 | $10.9M | Research |
| Electro Mechanical Solutions, Inc. | Manufacturing | $206,000 | $207,236 | 11 | <$5M | Research |
| Junius W Johnson Memorial Young Mens Christian Association | Arts, Entertainment, and Recreation | $205,770 | $207,428 | 264 | $37.0M | Research |
| Forbes 5 Relocation Specialist LLC | Transportation and Warehousing | $205,597 | $206,761 | 10 | <$5M | Research |
| Private Home Care Inc. | Health Care and Social Assistance | $203,598 | $206,181 | 52 | $8.9M | Research |
| 10 South LLC | Accommodation and Food Services | $203,400 | $204,705 | 51 | $6.2M | Research |
| Hannon's Food Service of Vicksburg, Inc. | Accommodation and Food Services | $196,000 | $198,564 | 45 | $8.0M | Research |
| Porter's Chapel Academy Inc. | Educational Services | $193,165 | $195,742 | 45 | N/A | Research |
| Porter's Chapel Academy, Inc. | Educational Services | $193,165 | $195,150 | 45 | N/A | Research |
| Delish! Brands | Accommodation and Food Services | $191,880 | $193,431 | 28 | <$5M | Research |
| Bridgers, Goodman, Baird & Clarke, Pllc | Professional, Scientific, and Technical Services | $189,500 | $190,512 | 25 | $8.0M | Research |
| Vicksburg Animal Hospital, P.a. | Professional, Scientific, and Technical Services | $181,775 | $182,982 | 23 | <$5M | Research |
| Southern Hospitality Services LLC | Accommodation and Food Services | $181,280 | $183,037 | 26 | $8.1M | Research |
| Rusty's Riverfront Grill, Inc. | Accommodation and Food Services | $179,900 | $182,124 | 20 | <$5M | Research |
| Cottonwood Public House LLC | Accommodation and Food Services | $176,575 | $178,493 | 29 | $5.1M | Research |
| Shriji Vicksburg LLC | Accommodation and Food Services | $171,153 | $172,771 | 26 | $8.1M | Research |
| Alabamafit Ar LLC | Arts, Entertainment, and Recreation | $167,396 | $169,401 | 43 | $6.0M | Research |
| Alabamafit Ar, LLC | Arts, Entertainment, and Recreation | $167,395 | $168,523 | 43 | $6.0M | Research |
| Sheffield Rentals Inc. | Real Estate and Rental and Leasing | $165,305 | $166,329 | 33 | $14.9M | Research |
| Super Junior of Vicksburg INC | Retail Trade | $164,110 | $165,678 | 35 | $11.7M | Research |
| Private Home Care INC | Health Care and Social Assistance | $163,190 | $164,106 | 98 | $16.8M | Research |
| Oasis Pools and Spas, INC | Retail Trade | $162,100 | $130,583 | 17 | <$5M | Research |
| Walnut Hills INC | Accommodation and Food Services | $160,126 | $161,211 | 25 | <$5M | Research |