| Yalobusha General Hospital and Nursing Home | Health Care and Social Assistance | $2,404,500 | $2,430,917 | 368 | N/A |  Research |
| Valley Tool INC | Manufacturing | $883,883 | $889,283 | 98 | $25.7M | Research |
| Valley Tool, Inc. | Manufacturing | $873,500 | $880,368 | 112 | $29.3M | Research |
| Cornerstone Business Associates, Inc. | Health Care and Social Assistance | $344,000 | $346,300 | 38 | $10.3M | Research |
| Cornerstone Business Associates INC | Health Care and Social Assistance | $334,854 | $337,909 | 38 | $10.3M | Research |
| Marchbanks Specialty Company, Inc. | Construction | $260,900 | $262,344 | 24 | $7.9M | Research |
| Marchbanks Specialty Company, Inc. | Construction | $258,995 | $261,330 | 23 | $7.8M | Research |
| D & S Haulers, LLC | Transportation and Warehousing | $234,900 | $221,381 | 23 | <$5M | Research |
| Larson's Grocery of Water Valley INC | Retail Trade | $230,100 | $219,449 | 58 | $14.5M | Research |
| D & S Haulers, LLC | Transportation and Warehousing | $220,080 | $221,187 | 19 | <$5M | Research |
| Tg Baker Trucking, Inc. | Transportation and Warehousing | $180,900 | $182,985 | 25 | $5.0M | Research |
| Mid South Communications Inc. | Construction | $137,940 | $138,730 | 23 | $7.1M | Research |
| C W White INC | Wholesale Trade | $133,200 | $134,521 | 25 | $6.4M | Research |
| Turnage Drug Store Inc. | Manufacturing | $105,000 | $105,849 | 13 | $12.9M | Research |
| El Charrito Inc. | Accommodation and Food Services | $86,863 | $87,338 | 12 | <$5M | Research |
| Lee Pullen Dental Dmd PA | Manufacturing | $82,700 | $83,391 | 13 | <$5M | Research |
| Hills Construction LLC | Construction | $78,300 | $79,173 | 10 | $11.4M | Research |
| Sonic Drive-In, Water Valley, Ms, LLC | Accommodation and Food Services | $74,250 | $75,332 | 46 | $8.2M | Research |
| Pass Termite and Pest Control | Administrative and Support and Waste Management | $72,500 | $73,108 | 9 | <$5M | Research |
| Her Trucking, Inc. | Transportation and Warehousing | $68,600 | $69,374 | 6 | <$5M | Research |
| Crowmartin Pllc | Professional, Scientific, and Technical Services | $66,200 | $66,594 | 4 | <$5M | Research |
| Mills Planting Company Partnership | Agriculture, Forestry, Fishing and Hunting | $59,735 | $59,938 | 6 | <$5M | Research |
| Valley Sheet Metal Works | Manufacturing | $57,500 | $57,864 | 10 | <$5M | Research |
| Barry L. Weeks Dmd PC | Health Care and Social Assistance | $54,600 | $55,243 | 5 | <$5M | Research |
| Barry L Weeks Dmd PC | Health Care and Social Assistance | $54,587 | $54,928 | 5 | <$5M | Research |