| Midamerica Hotels Corporation | Accommodation and Food Services | $6,380,200 | $6,442,953 | 500 | $88.8M |  Research |
| Plaza Tire Service, Inc. | Retail Trade | $5,503,500 | $5,553,949 | 500 | $135.2M | Research |
| Drury Southwest INC | Accommodation and Food Services | $3,466,600 | $3,503,537 | 250 | $78.2M | Research |
| Community Counseling Center | Health Care and Social Assistance | $3,174,700 | $3,211,915 | 453 | N/A | Research |
| The Lutheran Home for the Aged | Health Care and Social Assistance | $3,039,400 | $3,075,207 | 428 | N/A | Research |
| Ypykya, Inc. | Accommodation and Food Services | $2,803,698 | $2,647,804 | 500 | $88.8M | Research |
| Auto Tire and Parts Co. INC | Wholesale Trade | $2,661,200 | $2,692,395 | 250 | $76.6M | Research |
| Concord Publishing House, INC | Information | $2,354,500 | $2,385,697 | 308 | $51.7M | Research |
| Pajco, INC | Retail Trade | $2,332,000 | $2,358,883 | 500 | $167.3M | Research |
| Drury Southwest INC | Accommodation and Food Services | $2,000,000 | $2,017,041 | 171 | $53.5M | Research |
| Concord Publishing House Inc. | Information | $2,000,000 | $2,014,778 | 294 | $49.4M | Research |
| Cape Retirement Community, Inc. | Health Care and Social Assistance | $1,446,342 | $1,462,292 | 205 | N/A | Research |
| Cape Radiology Group PC | Health Care and Social Assistance | $1,347,000 | $1,359,160 | 94 | $21.8M | Research |
| Auburn Investments Inc. | Accommodation and Food Services | $1,340,526 | $1,357,199 | 126 | $39.4M | Research |
| Landmark Hospital of Cape Girardeau | Health Care and Social Assistance | $1,220,500 | $1,227,314 | 107 | $21.2M | Research |
| Cross Trails Medical Center | Health Care and Social Assistance | $1,101,000 | $1,111,286 | 86 | N/A | Research |
| Missouri Med LLC | Wholesale Trade | $1,097,000 | $93,117 | 15 | <$5M | Research |
| Artisan Contracting LLC | Construction | $1,092,400 | $1,101,746 | 47 | $53.5M | Research |
| Kt Power Systems Inc. | Construction | $972,732 | $978,542 | 51 | $16.8M | Research |
| Kt Power Systems, Inc. | Construction | $972,700 | $978,212 | 51 | $16.8M | Research |
| Zimmer Radio of Mid-Missouri, Inc. | Information | $957,300 | $969,639 | 134 | $22.5M | Research |
| Tri State Water Treatment Inc. | Construction | $851,200 | $856,449 | 90 | $29.6M | Research |
| Electrical Contractors, Inc. | Construction | $846,700 | $851,919 | 54 | $17.8M | Research |
| Oz Arc/gas Equipment & Supply, Inc. | Wholesale Trade | $821,400 | $826,175 | 70 | $18.0M | Research |
| Red Letter Communications INC | Professional, Scientific, and Technical Services | $790,763 | $795,442 | 55 | $6.2M | Research |