| Ttg, Inc. | Manufacturing | $705,000 | $711,835 | 64 | $63.5M |  Research |
| George J & Hilda Meyer Foundation, Inc. | Health Care and Social Assistance | $637,400 | $640,923 | 114 | N/A | Research |
| Lafayette Co Truck & Tractor | Retail Trade | $257,800 | $259,282 | 30 | <$5M | Research |
| Heins Family Farms, LLC | Agriculture, Forestry, Fishing and Hunting | $244,100 | $245,910 | 20 | <$5M | Research |
| C&s Construction Grain Bin Services LLC | Construction | $228,700 | $249,725 | 23 | $26.2M | Research |
| Heins Family Farms LLC | Agriculture, Forestry, Fishing and Hunting | $215,204 | $216,244 | 21 | <$5M | Research |
| Earthworks Excavation LLC | Construction | $190,882 | $192,054 | 20 | $6.2M | Research |
| Country Mart of Higginsville, LLC | Retail Trade | $170,580 | $171,618 | 41 | $10.2M | Research |
| Earthworks Excavation LLC | Construction | $165,315 | $166,385 | 17 | $5.3M | Research |
| The Cornerstone Agency, Inc. | Finance and Insurance | $155,000 | $155,753 | 24 | $12.3M | Research |
| At Home Residential Services | Health Care and Social Assistance | $145,832 | $146,456 | 30 | $5.1M | Research |
| L & M Kleinschmidt's, LLC | Retail Trade | $138,539 | $139,735 | 21 | $6.4M | Research |
| At Home Residential Services, INC | Health Care and Social Assistance | $129,735 | $131,483 | 30 | $5.1M | Research |
| Gash Plumbing LLC | Construction | $120,763 | $122,155 | 12 | <$5M | Research |
| Bf Companies, LLC | Manufacturing | $119,700 | $121,230 | 16 | <$5M | Research |
| Banner Coulson Chevrolet LLC | Retail Trade | $114,600 | $115,826 | 30 | $7.6M | Research |
| Gash Plumbing LLC | Construction | $114,360 | $115,742 | 12 | <$5M | Research |
| Hoflander Ford, Inc. | Retail Trade | $113,500 | $114,262 | 11 | <$5M | Research |
| Timothy H Thurmon, Certified Public Accountant, P.c. | Professional, Scientific, and Technical Services | $109,726 | $110,482 | 6 | <$5M | Research |
| Hughes Automotive INC | Retail Trade | $103,572 | $104,257 | 12 | <$5M | Research |
| Immanuel Lutheran Church | Other Services (except Public Administration) | $94,250 | $94,643 | 19 | N/A | Research |
| Lafayette County Enterprise | Health Care and Social Assistance | $93,795 | $94,272 | 47 | $7.6M | Research |
| Alumbaugh, Inc. | Construction | $93,306 | $93,855 | 10 | <$5M | Research |
| Lafayette County Enterprises I | Public Administration | $84,700 | $85,321 | 48 | N/A | Research |
| Timothy H Thurmon, Certified Public Accountant, P.c. | Professional, Scientific, and Technical Services | $84,605 | $85,159 | 6 | <$5M | Research |