| John Fitzgibbon Memorial Hospital, Inc. | Health Care and Social Assistance | $5,168,114 | $5,228,983 | 444 | N/A |  Research |
| Missouri Valley College | Educational Services | $2,245,997 | $2,268,894 | 464 | N/A | Research |
| Central Missouri Agriservice LLC | Wholesale Trade | $1,570,600 | $1,566,634 | 102 | $26.3M | Research |
| Central Missouri Agriservice LLC | Agriculture, Forestry, Fishing and Hunting | $1,549,613 | $1,562,870 | 106 | $5.3M | Research |
| Mik-Di Enterprises INC | Accommodation and Food Services | $1,230,600 | $1,238,770 | 174 | $30.9M | Research |
| Ag Solutions Group LLC | Wholesale Trade | $1,006,000 | $1,017,821 | 85 | $21.9M | Research |
| Kays Engineering, Inc. | Manufacturing | $790,125 | $795,041 | 60 | $15.7M | Research |
| Marshall Electric Contracting, Inc. | Construction | $538,522 | $543,817 | 44 | $14.5M | Research |
| Marshall Electric Contracting INC | Construction | $538,522 | $542,022 | 42 | $13.8M | Research |
| Common Good Natural Living LLC | Health Care and Social Assistance | $522,729 | $525,546 | 79 | $13.4M | Research |
| Common Good Natural Living, LLC | Health Care and Social Assistance | $481,500 | $486,649 | 84 | $13.6M | Research |
| Red Cross Pharmacy, Inc. | Health Care and Social Assistance | $405,100 | $407,846 | 71 | $13.0M | Research |
| Hahn & Phillips Grease Co INC | Manufacturing | $337,641 | $340,576 | 29 | $10.2M | Research |
| Hahn & Phillips Grease Co INC | Manufacturing | $335,054 | $336,822 | 32 | $11.3M | Research |
| Mid-State Seeds, LLC | Manufacturing | $323,869 | $325,164 | 29 | $10.2M | Research |
| Mid-State Seeds, LLC | Manufacturing | $303,732 | $305,571 | 27 | $9.5M | Research |
| United Hog Systems, LLC | Agriculture, Forestry, Fishing and Hunting | $300,917 | $302,113 | 28 | <$5M | Research |
| Ham Hill Farms INC | Agriculture, Forestry, Fishing and Hunting | $299,993 | $301,660 | 26 | <$5M | Research |
| W. B. Young Co. Inc. | Construction | $291,197 | $292,249 | 21 | $7.2M | Research |
| W. B. Young Co., Inc. | Manufacturing | $290,900 | $294,358 | 21 | $5.5M | Research |
| Ham Hill Farms INC | Agriculture, Forestry, Fishing and Hunting | $284,370 | $286,266 | 28 | <$5M | Research |
| Marshall Chrysler Dodge LLC | Retail Trade | $257,100 | $259,007 | 29 | $7.3M | Research |
| United Hog Systems, LLC | Agriculture, Forestry, Fishing and Hunting | $257,022 | $258,743 | 30 | <$5M | Research |
| Swift Carriers, Inc. | Transportation and Warehousing | $248,597 | $250,020 | 22 | <$5M | Research |
| Mccarthy Cbg, INC | Retail Trade | $224,000 | $210,347 | 18 | <$5M | Research |