| J. C. Shoemyer, Inc. | Wholesale Trade | $1,629,939 | $824,028 | 107 | $32.8M |  Research |
| Dmp Fin. Co. LLC | Manufacturing | $869,757 | $873,927 | 28 | $7.8M | Research |
| Dmp Fin. Co., LLC | Manufacturing | $673,500 | $679,880 | 36 | $8.8M | Research |
| George C Potterfield Trucking INC | Transportation and Warehousing | $466,692 | $470,335 | 42 | $8.5M | Research |
| Lakeside Casting Solutions | Manufacturing | $413,567 | $416,784 | 58 | $15.2M | Research |
| Learning Opportunities/quality Works INC | Health Care and Social Assistance | $402,925 | $404,492 | 84 | N/A | Research |
| Monroe City Manor Care Center | Health Care and Social Assistance | $366,984 | $369,849 | 75 | $12.8M | Research |
| Learning Opportunities/quality Works INC | Health Care and Social Assistance | $350,000 | $341,512 | 63 | N/A | Research |
| Ren Potterfield Trucking, Inc. | Transportation and Warehousing | $331,396 | $334,020 | 34 | $6.9M | Research |
| Two Mile Pork LLC | Agriculture, Forestry, Fishing and Hunting | $291,822 | $293,639 | 37 | $6.1M | Research |
| Two Mile Pork, LLC | Agriculture, Forestry, Fishing and Hunting | $266,182 | $267,817 | 34 | $5.6M | Research |
| Farmers Elevator & Exchange Co | Transportation and Warehousing | $255,562 | $257,585 | 28 | $7.1M | Research |
| Holy Rosary Catholic Church, Monroe City | Other Services (except Public Administration) | $154,100 | $154,969 | 20 | N/A | Research |
| Gosney Pharmacy, Inc. | Manufacturing | $140,000 | $72,442 | 9 | $8.9M | Research |
| Joshua L Potterfield Trucking INC | Transportation and Warehousing | $134,063 | $134,599 | 12 | <$5M | Research |
| Joshua L Potterfield Trucking INC | Transportation and Warehousing | $115,673 | $116,566 | 9 | <$5M | Research |
| Hassard Elevator Co | Transportation and Warehousing | $97,560 | $113,326 | 21 | $5.3M | Research |
| Quinn Farm Supply Inc. | Retail Trade | $77,528 | $78,133 | 8 | <$5M | Research |
| Quinn Farm Supply INC | Wholesale Trade | $77,528 | $77,881 | 3 | <$5M | Research |
| Gvc Consultants LLC | Professional, Scientific, and Technical Services | $75,738 | $76,147 | 6 | <$5M | Research |
| Moo-Shine's LLC | Accommodation and Food Services | $70,000 | $7,297 | 15 | <$5M | Research |
| Ricketts Farm Service of Mc, LLC | Wholesale Trade | $69,200 | $69,863 | 8 | <$5M | Research |
| Indian Creek Development Corp | Arts, Entertainment, and Recreation | $67,490 | $67,947 | 17 | <$5M | Research |
| Monroe City Sheltered Workshop | Health Care and Social Assistance | $67,046 | $67,316 | 51 | N/A | Research |
| Vollrathbenson LLC | Retail Trade | $66,955 | $67,357 | 7 | <$5M | Research |