| Bootheel In-Home Care Services, LLC | Health Care and Social Assistance | $721,000 | $725,998 | 234 | $40.1M | AI Deep Dive |
| Family Matters Home Services LLC | Health Care and Social Assistance | $699,400 | $705,209 | 158 | $27.1M | AI Deep Dive |
| N & R of New Madrid LLC | Health Care and Social Assistance | $385,100 | $389,521 | 93 | $15.8M | AI Deep Dive |
| Family Matters Cds LLC | Health Care and Social Assistance | $126,870 | $127,189 | 84 | $14.4M | AI Deep Dive |
| Martindale Chevrolet INC | Retail Trade | $105,179 | $105,915 | 15 | <$5M | AI Deep Dive |
| Martindale Chevrolet, Inc. | Retail Trade | $105,000 | $105,840 | 15 | <$5M | AI Deep Dive |
| Family Matters Cds LLC | Health Care and Social Assistance | $102,500 | $103,160 | 77 | $13.2M | AI Deep Dive |
| Bootheel Cotton Co | Agriculture, Forestry, Fishing and Hunting | $91,360 | $91,818 | 30 | <$5M | AI Deep Dive |
| New Madrid Pharmacy, Inc. | Retail Trade | $81,588 | $82,274 | 11 | <$5M | AI Deep Dive |
| A. C. Riley Cotton Company LLC | Agriculture, Forestry, Fishing and Hunting | $69,465 | $69,722 | 5 | <$5M | AI Deep Dive |
| Ac Riley Cotton Co, LLC | Agriculture, Forestry, Fishing and Hunting | $66,102 | $54,803 | 6 | <$5M | AI Deep Dive |
| Ryan Riley | Agriculture, Forestry, Fishing and Hunting | $64,680 | $64,955 | 11 | <$5M | AI Deep Dive |
| Timothy Rausch Dmd | Health Care and Social Assistance | $59,592 | $60,065 | 8 | <$5M | AI Deep Dive |
| Timothy Rausch | Health Care and Social Assistance | $50,000 | $50,215 | 7 | <$5M | AI Deep Dive |
| Immaculate Conception Parish | Other Services (except Public Administration) | $49,178 | $49,456 | 10 | N/A | AI Deep Dive |
| Ling Farms LLC | Agriculture, Forestry, Fishing and Hunting | $48,919 | $49,120 | 8 | <$5M | AI Deep Dive |
| Hunter Law Firm LLP | Professional, Scientific, and Technical Services | $46,491 | $46,779 | 3 | <$5M | AI Deep Dive |
| Hunter Law Firm, LLP | Professional, Scientific, and Technical Services | $46,491 | $46,772 | 3 | <$5M | AI Deep Dive |
| John Paul Wescoat Farms | Agriculture, Forestry, Fishing and Hunting | $44,700 | $44,957 | 7 | <$5M | AI Deep Dive |
| Tjt Lawfield Farms | Agriculture, Forestry, Fishing and Hunting | $44,700 | $44,951 | 7 | <$5M | AI Deep Dive |
| Ling Farms LLC | Agriculture, Forestry, Fishing and Hunting | $43,400 | $43,761 | 5 | <$5M | AI Deep Dive |
| Jessie Sullenger Farms, LLC | Agriculture, Forestry, Fishing and Hunting | $39,777 | $40,049 | 5 | <$5M | AI Deep Dive |
| Jessie Sullenger Farms LLC | Agriculture, Forestry, Fishing and Hunting | $39,777 | $40,007 | 5 | <$5M | AI Deep Dive |
| Angela Clayton | Retail Trade | $38,801 | $39,006 | 10 | <$5M | AI Deep Dive |
| Mark Baker | Agriculture, Forestry, Fishing and Hunting | $38,740 | $38,943 | 4 | <$5M | AI Deep Dive |