| Cohen Architectural Woodworking, LLC | Manufacturing | $759,154 | $766,176 | 78 | $20.4M |  Research |
| Cohen Architectural Woodworking LLC | Manufacturing | $745,969 | $752,662 | 71 | $18.6M | Research |
| Excel Utility Contractors, LLC | Manufacturing | $716,100 | $724,634 | 61 | $16.0M | Research |
| Prock Operations, INC | Retail Trade | $644,700 | $649,964 | 120 | $30.0M | Research |
| St James Winery INC | Manufacturing | $631,507 | $639,278 | 89 | $31.4M | Research |
| St. James Transports, Llc. | Transportation and Warehousing | $615,907 | $621,946 | 55 | $14.7M | Research |
| Hutcheson Ford Sales, LLC | Retail Trade | $607,500 | $612,613 | 45 | $11.3M | Research |
| Prock Operations Inc. | Manufacturing | $578,750 | $584,316 | 65 | $64.5M | Research |
| Central Missouri Transfer, LLC | Administrative and Support and Waste Management | $434,003 | $438,222 | 41 | $7.8M | Research |
| St. James Auto & Truck Parts, LLC | Wholesale Trade | $359,660 | $362,178 | 43 | $13.2M | Research |
| N&r of St. James, LLC | Health Care and Social Assistance | $329,765 | $333,640 | 64 | $10.9M | Research |
| Gahr Truck and Equipment, Inc. | Manufacturing | $297,805 | $299,873 | 30 | $7.9M | Research |
| The Public House Brewing Co LLC | Accommodation and Food Services | $241,252 | $243,349 | 26 | <$5M | Research |
| Sybill's Antiques & Fine Gifts Inc. | Accommodation and Food Services | $230,906 | $232,058 | 37 | $6.6M | Research |
| Forest City Pharmacy, L.l.c | Retail Trade | $190,648 | $192,480 | 23 | <$5M | Research |
| Msc Endeavors LLC | Transportation and Warehousing | $180,750 | $182,467 | 20 | <$5M | Research |
| The Public House Brewing Co, LLC | Accommodation and Food Services | $165,986 | $168,029 | 41 | $5.0M | Research |
| Sybill's Antiques & Fine Gifts INC | Accommodation and Food Services | $165,901 | $167,065 | 40 | $7.1M | Research |
| R.d. Wilkerson D.m.d. P.c. | Health Care and Social Assistance | $153,765 | $154,585 | 16 | <$5M | Research |
| Avidity Corporation | Manufacturing | $149,300 | $150,312 | 12 | <$5M | Research |
| St. James Oil Company, LLC | Wholesale Trade | $146,735 | $125,701 | 13 | <$5M | Research |
| R.d. Wilkerson, D.m.d., P.c. | Health Care and Social Assistance | $141,290 | $142,491 | 15 | <$5M | Research |
| Cardetti Heritage LLC | Accommodation and Food Services | $131,613 | $132,253 | 19 | <$5M | Research |
| L. Davis Transports, L.l.c. | Transportation and Warehousing | $130,136 | $130,989 | 13 | <$5M | Research |
| Country Bob's Hometown Cafe LLC | Accommodation and Food Services | $122,125 | $122,731 | 27 | <$5M | Research |