| Linneman/vetter/sanders, LLC | Construction | $316,211 | $318,862 | 39 | $9.0M | Research |
| Ricketts Farm Service INC | Wholesale Trade | $301,585 | $303,755 | 25 | $6.4M | Research |
| Salisbury Ag Center, INC | Wholesale Trade | $178,300 | $179,697 | 19 | <$5M | Research |
| St. Joseph Catholic Church, Salisbury | Other Services (except Public Administration) | $134,300 | $135,065 | 30 | N/A | Research |
| Air Link Rural Broadband, LLC | Information | $122,284 | $122,974 | 14 | <$5M | Research |
| Wrights Oil Service INC | Retail Trade | $118,879 | $119,315 | 12 | <$5M | Research |
| Wright's Oil Service INC | Retail Trade | $118,800 | $118,767 | 12 | <$5M | Research |
| Agrivision Solutions LLC | Agriculture, Forestry, Fishing and Hunting | $101,200 | $102,129 | 8 | <$5M | Research |
| Chariton Tire, LLC | Retail Trade | $86,650 | $87,300 | 13 | <$5M | Research |
| Richard Brown, LLC | Retail Trade | $79,973 | $80,619 | 8 | <$5M | Research |
| M&m Trucking & Reclamation INC | Transportation and Warehousing | $74,898 | $75,234 | 8 | <$5M | Research |
| Salisbury Foods INC | Retail Trade | $72,405 | $72,945 | 18 | <$5M | Research |
| Chariton Health Systems, Inc. | Real Estate and Rental and Leasing | $64,906 | $65,441 | 12 | $5.4M | Research |
| Greg Asbury | Other Services (except Public Administration) | $62,875 | $63,092 | 5 | <$5M | Research |
| M&m Trucking & Reclamation, Inc. | Administrative and Support and Waste Management | $60,239 | $60,794 | 8 | <$5M | Research |
| Howard Ratliff Farms | Agriculture, Forestry, Fishing and Hunting | $59,030 | $59,578 | 3 | <$5M | Research |
| Salisbury Meat Market and Processing, LLC | Retail Trade | $58,315 | $58,694 | 9 | <$5M | Research |
| Bossville Wholesalers, Inc. | Wholesale Trade | $51,857 | $52,314 | 5 | <$5M | Research |
| Don Hinkle Trucking LLC | Transportation and Warehousing | $39,752 | $40,000 | 5 | <$5M | Research |
| Don Hinkle Trucking LLC | Transportation and Warehousing | $39,752 | $39,984 | 4 | <$5M | Research |
| Kent D Harmon | Agriculture, Forestry, Fishing and Hunting | $39,457 | $39,698 | 5 | <$5M | Research |
| Summerville Funeral Home INC | Other Services (except Public Administration) | $38,063 | $38,251 | 2 | <$5M | Research |
| Lois A. Duncan Cpa, LLC | Professional, Scientific, and Technical Services | $37,855 | $38,099 | 8 | <$5M | Research |
| Scott Moore | Construction | $37,435 | $37,612 | 4 | <$5M | Research |
| Rustemeyer Plumbing and Heating LLC | Construction | $37,145 | $37,385 | 4 | <$5M | Research |