| Alan Wire Co., Inc. | Manufacturing | $3,408,200 | $3,444,175 | 250 | $61.1M | Research |
| Health Facilities Rehab Services, INC | Health Care and Social Assistance | $2,611,500 | $2,641,895 | 242 | $41.2M | Research |
| S. & J. Potashnick Transportation, Inc. | Transportation and Warehousing | $2,339,400 | $2,249,167 | 245 | $49.4M | Research |
| Steward Steel, Inc. | Manufacturing | $1,509,200 | $1,517,847 | 120 | $29.3M | Research |
| Burch Food Services INC | Accommodation and Food Services | $1,373,700 | $1,381,713 | 186 | $34.7M | Research |
| Semo Electric Cooperative | Construction | $1,283,300 | $1,297,238 | 57 | $17.7M | Research |
| Mid States, INC | Health Care and Social Assistance | $1,227,500 | $1,241,787 | 74 | $12.6M | Research |
| Lamberts Cafe INC | Accommodation and Food Services | $1,056,685 | $1,068,925 | 91 | $16.2M | Research |
| Countryside Christian Church of Maryville Missouri | Health Care and Social Assistance | $1,047,789 | $1,055,764 | 116 | N/A | Research |
| Semo Express LLC | Transportation and Warehousing | $913,500 | $915,860 | 105 | $21.2M | Research |
| Lambert's Cafe, Inc. | Accommodation and Food Services | $808,000 | $814,599 | 91 | $16.2M | Research |
| Floyd's Equipment Inc. | Construction | $771,316 | $776,244 | 61 | $20.8M | Research |
| Construction Trailer Specialists, Inc. | Manufacturing | $750,000 | $754,130 | 68 | $17.8M | Research |
| Floyd's Equipment, Inc. | Construction | $739,200 | $744,046 | 68 | $77.5M | Research |
| The Dewitt Company Inc. | Wholesale Trade | $738,600 | $745,905 | 75 | $19.3M | Research |
| Physicians Park Pharmacy | Health Care and Social Assistance | $735,000 | $742,085 | 95 | $16.2M | Research |
| Semo Express, LLC | Transportation and Warehousing | $701,100 | $705,209 | 105 | $15.9M | Research |
| Kingman No 1, LLC | Health Care and Social Assistance | $572,700 | $579,180 | 92 | $15.7M | Research |
| Armor Lite Trailer Manufacturing, LLC | Manufacturing | $523,700 | $527,162 | 54 | $14.1M | Research |
| SE Energy LLC | Construction | $486,600 | $488,398 | 17 | $5.6M | Research |
| Havasu Nursing Center #2, INC | Health Care and Social Assistance | $478,200 | $483,611 | 76 | $12.9M | Research |
| Preferred Hospice of Missouri, LLC | Health Care and Social Assistance | $474,500 | $477,464 | 91 | $15.6M | Research |
| Lamar No. 1, INC | Health Care and Social Assistance | $459,000 | $464,368 | 100 | $17.0M | Research |
| Delta South Skilled Nursing & Rehabilitation LLC | Health Care and Social Assistance | $454,193 | $455,761 | 66 | $11.2M | Research |
| Ava No 1, INC | Health Care and Social Assistance | $448,200 | $453,271 | 93 | $15.8M | Research |