| The Loft Event Center and Music | Accommodation and Food Services | $367,946 | $369,643 | 40 | $7.1M |  Research |
| Earthworks, INC | Construction | $361,100 | $363,259 | 25 | $9.4M | Research |
| Comley Excavating Company LLC | Construction | $360,037 | $362,487 | 24 | $7.4M | Research |
| Comley Excavating Company LLC | Administrative and Support and Waste Management | $338,200 | $340,398 | 24 | $5.2M | Research |
| Earthworks INC | Manufacturing | $328,912 | $330,642 | 26 | $6.8M | Research |
| Controlled Fuidics, LLC | Manufacturing | $325,000 | $327,493 | 24 | $23.8M | Research |
| Fieldstone Land Consultants, Pllc | Professional, Scientific, and Technical Services | $305,500 | $307,460 | 18 | <$5M | Research |
| Milford Lumber Company | Retail Trade | $303,400 | $307,182 | 28 | $5.8M | Research |
| The Loft Event Center and Music Hall Corporation | Accommodation and Food Services | $301,700 | $303,560 | 40 | $7.1M | Research |
| Giorgios Ristorante Corp | Accommodation and Food Services | $267,813 | $270,685 | 35 | $6.2M | Research |
| Fieldstone Land Consultants, Pllc | Professional, Scientific, and Technical Services | $264,630 | $265,564 | 21 | <$5M | Research |
| Adam Vaillancourt Roofing & Construction LLC | Construction | $264,200 | $265,619 | 17 | $5.6M | Research |
| Advanced Gas Distributors | Retail Trade | $263,400 | $161,423 | 10 | <$5M | Research |
| Granite State Veterinary Associates, LLC DBA Milford Veteri | Professional, Scientific, and Technical Services | $259,500 | $214,176 | 19 | <$5M | Research |
| New Banks Boston INC | Professional, Scientific, and Technical Services | $247,673 | $248,443 | 14 | <$5M | Research |
| Demand Transport LLC | Transportation and Warehousing | $230,000 | $233,041 | 17 | $6.6M | Research |
| Tech Resources, Inc. | Manufacturing | $225,800 | $227,458 | 19 | <$5M | Research |
| Newbanks Boston, Inc. | Professional, Scientific, and Technical Services | $220,900 | $222,373 | 12 | <$5M | Research |
| G&s Motorsports, LLC | Retail Trade | $218,500 | $220,040 | 14 | <$5M | Research |
| Boys and Girls Club of Souhegan Valley, Inc. | Other Services (except Public Administration) | $217,000 | $219,134 | 24 | N/A | Research |
| Anrik Irrigation Inc. | Utilities | $212,300 | $108,693 | 14 | N/A | Research |
| Giorgios Ristorante Corp | Accommodation and Food Services | $210,468 | $203,428 | 34 | $6.0M | Research |
| Boys & Girls Club of Souhegan Valley | Health Care and Social Assistance | $205,500 | $208,035 | 21 | N/A | Research |
| Sanford Temperature Control INC | Construction | $193,500 | $196,136 | 12 | <$5M | Research |
| Turnstone Corporation | Construction | $190,800 | $193,116 | 14 | $16.0M | Research |