| Benson Woodworking Co, INC | Manufacturing | $1,333,287 | $1,345,250 | 112 | $111.1M | Research |
| Walpole Handmade Chocolates LLC | Manufacturing | $1,146,123 | $1,151,179 | 130 | $45.9M | Research |
| Walpole Handmade Chocolates, LLC | Retail Trade | $960,200 | $968,434 | 147 | $16.3M | Research |
| Frank W. Whitcomb Construction Corp. | Construction | $896,857 | $902,637 | 80 | $24.8M | Research |
| Chamberlain Machine LLC | Manufacturing | $824,152 | $833,149 | 58 | $14.2M | Research |
| The Hemingway Film Project, LLC | Information | $412,300 | $416,344 | 17 | <$5M | Research |
| Pinnacleview Equipment, Inc. | Wholesale Trade | $318,900 | $320,666 | 21 | $6.4M | Research |
| Cold River Bridges | Construction | $285,100 | $287,896 | 16 | <$5M | Research |
| Everett E. Houghton Co., INC | Construction | $227,200 | $229,111 | 23 | $7.3M | Research |
| Hicks Machine INC | Manufacturing | $226,200 | $228,208 | 16 | <$5M | Research |
| Everett E. Houghton Co. Inc. | Construction | $223,944 | $225,429 | 23 | $7.6M | Research |
| Peter L Bowman, DDS Family Dentistry Pllc | Health Care and Social Assistance | $215,200 | $217,305 | 15 | <$5M | Research |
| Peter Bowman | Health Care and Social Assistance | $215,200 | $216,456 | 16 | <$5M | Research |
| Burns & Goins, LLC | Retail Trade | $210,300 | $212,017 | 30 | <$5M | Research |
| American Documentaries, Inc. | Information | $206,500 | $207,643 | 10 | <$5M | Research |
| The Muhammad Ali Film Project, LLC | Information | $200,800 | $202,769 | 8 | <$5M | Research |
| Walpole Veterinary Hospital, Inc. | Professional, Scientific, and Technical Services | $157,500 | $158,391 | 20 | <$5M | Research |
| The Mental Health Film Projects, LLC | Information | $105,300 | $105,946 | 6 | <$5M | Research |
| Fuzzy Brothers LLC | Construction | $97,100 | $98,321 | 12 | <$5M | Research |
| Connecticut Valley Yard Works | Administrative and Support and Waste Management | $96,500 | $97,216 | 13 | <$5M | Research |
| Dooley Nielsen Associates Inc. | Administrative and Support and Waste Management | $93,029 | $93,715 | 6 | <$5M | Research |
| Dooley Nielsen Associates, Inc. | Administrative and Support and Waste Management | $93,000 | $93,567 | 7 | <$5M | Research |
| Hodgkins & Sons INC | Construction | $90,545 | $91,051 | 10 | <$5M | Research |
| Bellows House, Inc. | Manufacturing | $88,200 | $89,063 | 9 | <$5M | Research |
| Fuzzy Brothers LLC | Construction | $87,811 | $88,819 | 11 | <$5M | Research |