| New Mexico Wineries, Inc. | Manufacturing | $665,419 | $669,541 | 66 | $23.3M | Research |
| Plaza De Florida Ltd | Retail Trade | $598,338 | $601,678 | 72 | $18.0M | Research |
| Rocky Mountain Transportation INC | Transportation and Warehousing | $440,609 | $443,441 | 43 | $8.7M | Research |
| Rocky Mountain Transportation INC | Transportation and Warehousing | $408,173 | $409,963 | 39 | $7.9M | Research |
| Deming Coca-Cola Bottling Co. INC | Manufacturing | $340,078 | $342,370 | 30 | $10.6M | Research |
| Columbus Electric Cooperative INC | Utilities | $316,809 | $321,105 | 23 | N/A | Research |
| Sisbarro Deming, LLC | Retail Trade | $291,500 | $294,569 | 23 | $5.8M | Research |
| Deming Excavating INC | Construction | $277,400 | $278,957 | 39 | $14.6M | Research |
| Nutt Dairy LLC | Agriculture, Forestry, Fishing and Hunting | $264,965 | $267,519 | 24 | <$5M | Research |
| Luna Rossa Winery INC | Accommodation and Food Services | $256,459 | $257,562 | 20 | <$5M | Research |
| Carrillo Farm Labor LLC | Agriculture, Forestry, Fishing and Hunting | $250,000 | $251,712 | 60 | <$5M | Research |
| Billy the Kid Produce LLC | Agriculture, Forestry, Fishing and Hunting | $217,532 | $219,417 | 42 | <$5M | Research |
| Driven Fence Inc. | Construction | $210,987 | $212,464 | 14 | <$5M | Research |
| Billy the Kid Produce, LLC | Agriculture, Forestry, Fishing and Hunting | $200,060 | $201,449 | 127 | $13.0M | Research |
| Mimbres Internal Medicine PA | Health Care and Social Assistance | $197,639 | $198,890 | 18 | $5.6M | Research |
| Xavier Rios | Construction | $197,000 | $197,990 | 21 | $23.9M | Research |
| Luna Rossa Winery INC | Retail Trade | $183,185 | $184,379 | 45 | $6.9M | Research |
| Crg International | Construction | $163,900 | $164,829 | 12 | <$5M | Research |
| New Mexico Drip & Sprinkler INC | Construction | $160,955 | $161,793 | 19 | $5.9M | Research |
| 5r Travel Center, Inc. | Retail Trade | $139,000 | $139,784 | 27 | $9.0M | Research |
| Mimbres Valley Hospitality LLC | Accommodation and Food Services | $138,285 | $139,941 | 30 | $9.4M | Research |
| Montell Fabrication and Rebuild, LLC | Manufacturing | $138,033 | $129,729 | 13 | <$5M | Research |
| Keeler Family Farms LLC | Agriculture, Forestry, Fishing and Hunting | $134,173 | $134,768 | 13 | <$5M | Research |
| M & T Buses INC | Transportation and Warehousing | $132,395 | $133,360 | 35 | $13.5M | Research |
| Southwest Regional Housing and Cdc | Health Care and Social Assistance | $120,000 | $120,740 | 18 | N/A | Research |