| Dent Neurologic Group, LLP | Health Care and Social Assistance | $5,191,637 | $5,250,665 | 443 | $139.0M | Research |
| Stampede Presentation Products, Inc. | Wholesale Trade | $2,513,900 | $0 | 179 | $54.8M | Research |
| 1135 Millersport Highway LLC | Retail Trade | $2,000,000 | $1,643,662 | 204 | $51.4M | Research |
| Autism Services INC | Health Care and Social Assistance | $2,000,000 | $2,026,301 | 264 | N/A | Research |
| Buffalo Surgery Center, LLC | Health Care and Social Assistance | $1,476,700 | $1,493,166 | 104 | $18.5M | Research |
| Twin City Ambulance Corp. | Health Care and Social Assistance | $1,367,500 | $1,381,138 | 260 | $60.2M | Research |
| Advance 2000 INC | Professional, Scientific, and Technical Services | $1,352,997 | $1,368,895 | 92 | $19.0M | Research |
| Hoganwillig Pllc | Public Administration | $1,173,750 | $1,189,954 | 77 | N/A | Research |
| General Oil Equipment Co. Inc. | Manufacturing | $1,095,642 | $1,104,497 | 74 | $18.1M | Research |
| Uniland Development Corporation | Real Estate and Rental and Leasing | $1,088,815 | $1,096,302 | 64 | $11.7M | Research |
| 3930 Sd LLC | Retail Trade | $1,076,797 | $1,091,282 | 91 | $22.9M | Research |
| 3930 Sd, LLC | Retail Trade | $1,076,795 | $1,089,038 | 99 | $24.9M | Research |
| General Oil Equipment Co., INC | Manufacturing | $1,044,090 | $1,051,899 | 80 | $79.3M | Research |
| Reeds Jewelers of Niagara Falls Inc. | Retail Trade | $918,000 | $924,112 | 72 | $19.9M | Research |
| Atlas Painting and Sheeting Corp | Construction | $891,452 | $897,656 | 64 | $16.2M | Research |
| Stellar Dental Pllc | Health Care and Social Assistance | $869,817 | $877,109 | 52 | $12.0M | Research |
| Employer Services Corporation | Professional, Scientific, and Technical Services | $856,800 | $866,612 | 61 | $6.3M | Research |
| Ez Loan Auto Sales INC | Retail Trade | $856,587 | $879,046 | 72 | $18.1M | Research |
| Kalra Enterprises Inc. | Accommodation and Food Services | $851,406 | $860,200 | 135 | $24.0M | Research |
| Ambulatory Surgery Center of Western New York LLC | Health Care and Social Assistance | $817,997 | $826,692 | 99 | $17.6M | Research |
| Mjw Technical Services, Inc. | Professional, Scientific, and Technical Services | $795,312 | $804,616 | 46 | <$5M | Research |
| Ambulatory Surgery Center of Western New York LLC | Health Care and Social Assistance | $788,370 | $791,156 | 95 | $16.9M | Research |
| Law Offices of Kenneth Hiller Pllc | Professional, Scientific, and Technical Services | $750,637 | $755,470 | 58 | $14.1M | Research |
| Inspire Dental Group Pllc | Health Care and Social Assistance | $734,420 | $738,570 | 82 | $19.0M | Research |
| Inspire Dental Group Pllc | Health Care and Social Assistance | $734,420 | $737,901 | 82 | $19.0M | Research |