| Hearth Management, LLC | Health Care and Social Assistance | $7,775,717 | $7,914,615 | 500 | $81.0M |  Research |
| Learn As You Grow, Inc. | Health Care and Social Assistance | $863,667 | $870,411 | 136 | $22.0M | Research |
| Freight Management Group, INC | Transportation and Warehousing | $802,800 | $814,699 | 74 | $28.7M | Research |
| Associated Gastroenterologists of Cny PC | Health Care and Social Assistance | $753,830 | $756,804 | 61 | $19.1M | Research |
| Associated Gastroenterologist of Cny, PC | Health Care and Social Assistance | $753,750 | $757,901 | 62 | $19.5M | Research |
| Pulmonary Health Physicians, PC | Health Care and Social Assistance | $652,000 | $658,198 | 42 | $13.2M | Research |
| Preventive Medicine Associates Pllc | Health Care and Social Assistance | $379,325 | $383,492 | 32 | $10.0M | Research |
| Preventive Medicine Associates, Pllc | Health Care and Social Assistance | $379,325 | $383,513 | 32 | $10.0M | Research |
| Pediatric Associates LLP | Health Care and Social Assistance | $299,238 | $470,137 | 27 | $8.5M | Research |
| Gasparini Landscaping Co INC | Administrative and Support and Waste Management | $267,515 | $269,325 | 24 | $5.2M | Research |
| Western Area Volunteer Emergency Services, Inc. | Health Care and Social Assistance | $256,365 | $259,132 | 49 | N/A | Research |
| Epc LLC | Health Care and Social Assistance | $249,165 | $250,291 | 21 | <$5M | Research |
| Gasparini Landscaping Co., Inc. | Administrative and Support and Waste Management | $235,200 | $237,127 | 25 | $5.4M | Research |
| Advanced Ent Physicians & Surgeons of Central New York PC | Health Care and Social Assistance | $234,321 | $236,612 | 13 | <$5M | Research |
| Advanced Ent Physicians & Surgeons of Central New York PC | Health Care and Social Assistance | $234,320 | $236,435 | 22 | $6.9M | Research |
| Epc, LLC | Health Care and Social Assistance | $225,000 | $226,325 | 16 | $5.0M | Research |
| East View Associates LLC | Health Care and Social Assistance | $217,723 | $218,938 | 39 | $6.6M | Research |
| Robert K Druger MD Pllc | Health Care and Social Assistance | $205,827 | $208,494 | 20 | $6.3M | Research |
| Mark A. Paciorek, D.d.s., M.s., P.c. | Health Care and Social Assistance | $184,054 | $186,411 | 16 | <$5M | Research |
| West Asc LLC | Health Care and Social Assistance | $182,405 | $183,525 | 17 | <$5M | Research |
| Cameron Group LLC | Real Estate and Rental and Leasing | $173,925 | $175,307 | 9 | <$5M | Research |
| Robert K Druger MD Pllc | Health Care and Social Assistance | $170,152 | $171,630 | 109 | $34.2M | Research |
| Aesthetic Plastic Surgery of Syracuse Pllc | Health Care and Social Assistance | $165,602 | $167,654 | 11 | <$5M | Research |
| Aesthetic Plastic Surgery of Syracuse, Pllc | Health Care and Social Assistance | $165,602 | $167,157 | 11 | <$5M | Research |
| St. Germain & Aupperle Consulting Engineers, Pllc | Professional, Scientific, and Technical Services | $163,337 | $164,263 | 11 | <$5M | Research |