| Gary a Rosenfeld DDS PC | Health Care and Social Assistance | $784,777 | $787,873 | 49 | $11.4M | AI Deep Dive |
| Gary A. Rosenfeld, Dds, PC | Health Care and Social Assistance | $784,775 | $789,914 | 43 | $10.0M | AI Deep Dive |
| Keller Painting Corp | Construction | $729,405 | $737,199 | 48 | $12.1M | AI Deep Dive |
| Cross Country Computer Corp | Information | $677,800 | $687,026 | 43 | $7.2M | AI Deep Dive |
| Saint Marys R C Church | Other Services (except Public Administration) | $669,422 | $674,631 | 70 | N/A | AI Deep Dive |
| Cross Country Computer Corp | Information | $595,270 | $599,288 | 43 | $7.2M | AI Deep Dive |
| Premier Coin Galleries INC | Retail Trade | $555,615 | $562,406 | 47 | $7.3M | AI Deep Dive |
| Irish Coffee Pub Inc. | Accommodation and Food Services | $450,000 | $455,523 | 55 | $9.8M | AI Deep Dive |
| Vanguard Fire Suppression, LLC | Construction | $446,600 | $449,652 | 28 | $8.9M | AI Deep Dive |
| Roman Catholic Church of St Mary | Other Services (except Public Administration) | $429,900 | $433,928 | 76 | N/A | AI Deep Dive |
| East Islip Lumber | Retail Trade | $406,000 | $408,921 | 25 | $5.2M | AI Deep Dive |
| Sunrise Counseling Center Ltd. | Health Care and Social Assistance | $395,000 | $398,774 | 90 | $14.6M | AI Deep Dive |
| The Telecom Planning Corporation | Professional, Scientific, and Technical Services | $302,606 | $305,691 | 32 | <$5M | AI Deep Dive |
| Irish Coffee Pub, INC | Accommodation and Food Services | $290,000 | $294,124 | 50 | $8.9M | AI Deep Dive |
| Jones, Little & Co, Cpa's LLP | Professional, Scientific, and Technical Services | $278,528 | $282,110 | 24 | $7.6M | AI Deep Dive |
| The Telecom Planning Corporation | Professional, Scientific, and Technical Services | $238,832 | $241,804 | 22 | <$5M | AI Deep Dive |
| James F. Sutton Agency Ltd. | Finance and Insurance | $235,079 | $237,364 | 17 | $8.7M | AI Deep Dive |
| Broadhollow Players, Ltd. | Arts, Entertainment, and Recreation | $230,670 | $100,877 | 150 | $24.6M | AI Deep Dive |
| Vikas Desai, MD P.c. | Health Care and Social Assistance | $224,740 | $227,406 | 21 | $6.6M | AI Deep Dive |
| Beachtree Cafe of East Islip INC | Accommodation and Food Services | $219,977 | $222,928 | 48 | $8.5M | AI Deep Dive |
| Exclusive Interior Installations INC | Construction | $217,710 | $219,428 | 7 | <$5M | AI Deep Dive |
| 335 East Islip Restaurant Corp. | Accommodation and Food Services | $216,394 | $219,453 | 46 | $8.2M | AI Deep Dive |
| Lucchese Food Service LLC | Retail Trade | $201,582 | $186,239 | 29 | $7.2M | AI Deep Dive |
| Hart Insulation INC | Construction | $186,532 | $189,481 | 7 | <$5M | AI Deep Dive |
| Vikas Desai, MD P.c. | Health Care and Social Assistance | $182,200 | $184,052 | 19 | $6.0M | AI Deep Dive |