| Mo Dental As Judge Dds, P.c> | Health Care and Social Assistance | $10,000,000 | $0 | 500 | $115.9M | Research |
| Wellnow Urgent Care, P.c. | Health Care and Social Assistance | $10,000,000 | $0 | 500 | $156.9M | Research |
| Syracuse Orthopedic Specialists, P.c. | Health Care and Social Assistance | $7,874,060 | $7,976,099 | 500 | $156.9M | Research |
| Hematology-Oncology Associates of Cny, PC | Health Care and Social Assistance | $4,766,472 | $4,821,319 | 293 | $92.0M | Research |
| Mccarthy, William C. & David L | Other Services (except Public Administration) | $3,572,000 | $3,616,430 | 272 | $53.3M | Research |
| Tracey Road Equipment, Inc. | Wholesale Trade | $2,948,504 | $2,983,067 | 226 | $69.2M | Research |
| Pyramid Network Services LLC | Professional, Scientific, and Technical Services | $2,925,836 | $2,959,727 | 185 | $19.1M | Research |
| Mcintosh Box & Pallet Co., Inc. | Manufacturing | $2,492,972 | $2,521,814 | 407 | $403.7M | Research |
| Upstate Orthopedics, LLP | Health Care and Social Assistance | $2,140,060 | $2,164,334 | 170 | $53.4M | Research |
| Cny Family Care, LLP | Health Care and Social Assistance | $2,104,900 | $2,128,371 | 193 | $60.6M | Research |
| Thompson & Johnson Equipment Co., INC | Wholesale Trade | $2,103,900 | $2,127,994 | 163 | $49.9M | Research |
| Tracey Road Equipment | Wholesale Trade | $2,000,000 | $2,014,556 | 226 | $69.2M | Research |
| Mn Dentistry, PC | Health Care and Social Assistance | $1,990,021 | $0 | 102 | $23.6M | Research |
| Medical Management Resources, Inc. | Professional, Scientific, and Technical Services | $1,823,500 | $1,856,473 | 164 | $23.0M | Research |
| Medical Management Resources INC | Administrative and Support and Waste Management | $1,811,657 | $1,832,255 | 156 | $29.5M | Research |
| B.r. Johnson, LLC | Construction | $1,508,630 | $1,525,783 | 96 | $30.3M | Research |
| Chag Anesthesia, P.c. | Health Care and Social Assistance | $1,481,020 | $1,499,360 | 37 | $11.6M | Research |
| Prudent Engineering LLP | Professional, Scientific, and Technical Services | $1,417,632 | $1,436,547 | 73 | $9.0M | Research |
| East Syracuse Sales Co INC | Retail Trade | $1,417,184 | $1,430,890 | 104 | $26.2M | Research |
| B.r. Johnson LLC | Wholesale Trade | $1,417,177 | $1,426,923 | 81 | $24.8M | Research |
| Demco New York Corp. | Construction | $1,396,200 | $1,405,763 | 98 | $32.2M | Research |
| East Syracuse Sales Co INC | Retail Trade | $1,317,657 | $1,327,368 | 88 | $22.2M | Research |
| Chag Anesthesia P.c. | Health Care and Social Assistance | $1,285,909 | $1,297,887 | 48 | $15.1M | Research |
| Sky Testing Services INC | Professional, Scientific, and Technical Services | $1,173,720 | $1,185,811 | 100 | $14.0M | Research |
| Sky Testing Services, INC | Professional, Scientific, and Technical Services | $1,173,719 | $1,181,951 | 82 | $16.5M | Research |