| Big Red Shoes LLC | Accommodation and Food Services | $1,693,355 | $1,712,608 | 500 | $88.8M |  Research |
| Aspen Dental of Central New York Pllc | Health Care and Social Assistance | $1,063,062 | $1,070,372 | 103 | $23.9M | Research |
| Jdk Enterprises LLC | Accommodation and Food Services | $864,000 | $871,575 | 200 | $35.5M | Research |
| North Medical Cardiovascular Group | Health Care and Social Assistance | $819,797 | $829,971 | 68 | $21.3M | Research |
| Fayetteville Hotel Ownership LLC | Accommodation and Food Services | $807,502 | $812,616 | 79 | $24.7M | Research |
| Cor Development Company LLC | Real Estate and Rental and Leasing | $619,162 | $624,726 | 68 | $12.4M | Research |
| Cor Development Company, LLC | Real Estate and Rental and Leasing | $609,857 | $617,376 | 35 | $6.4M | Research |
| Kinsella Quarries | Mining, Quarrying, and Oil and Gas Extraction | $578,755 | $582,132 | 29 | <$5M | Research |
| Fayetteville Hotel Ownership LLC | Accommodation and Food Services | $576,787 | $585,166 | 88 | $27.5M | Research |
| Callahan, Flanagan and Smith Orthodontics | Health Care and Social Assistance | $486,100 | $488,870 | 39 | $9.0M | Research |
| Dermatology Associates of Central New York, Pllc | Health Care and Social Assistance | $470,336 | $475,825 | 38 | $11.9M | Research |
| Dr. Fazeli & Dr. Broumand LLC | Health Care and Social Assistance | $470,335 | $474,252 | 53 | $9.7M | Research |
| Fayetteville Dodge INC | Retail Trade | $465,414 | $471,153 | 38 | $9.6M | Research |
| Pediatric Dentistry and Interceptive Orthodontics, P.c. | Health Care and Social Assistance | $450,000 | $455,116 | 45 | $10.4M | Research |
| Vitkus Scutari & Cardoso Oral Surgery PC | Health Care and Social Assistance | $435,460 | $437,548 | 31 | $7.2M | Research |
| Pediatric Dentistry and Interceptive Orthodontics, P.c. | Health Care and Social Assistance | $388,150 | $392,691 | 45 | $10.4M | Research |
| Vitkus, Scutari, and Cardoso Oral Surgery, P.c. | Health Care and Social Assistance | $366,200 | $369,842 | 35 | $8.1M | Research |
| East Syracuse Cars, LLC | Retail Trade | $354,287 | $358,043 | 27 | $6.8M | Research |
| Onondaga Golf and Country Club | Arts, Entertainment, and Recreation | $338,602 | $341,125 | 109 | $15.3M | Research |
| East Syracuse Cars LLC | Retail Trade | $322,965 | $324,912 | 278 | $70.1M | Research |
| Gale Gale & Hunt LLC | Professional, Scientific, and Technical Services | $314,165 | $316,661 | 13 | <$5M | Research |
| Church of the Immaculate Conception | Other Services (except Public Administration) | $283,707 | $286,529 | 56 | N/A | Research |
| Cor West Kirkpatrick Street Company LLC | Accommodation and Food Services | $282,811 | $285,340 | 33 | $10.3M | Research |
| Arad Evans Inn INC | Accommodation and Food Services | $252,000 | $253,547 | 60 | $10.7M | Research |
| Empire Dermatology, Pllc | Health Care and Social Assistance | $245,300 | $247,632 | 20 | <$5M | Research |