| H.o. Penn Machinery Company Inc. | Retail Trade | $10,000,000 | $10,116,783 | 423 | $110.5M |  Research |
| Premier Medical Group of the Hudson Valley PC | Health Care and Social Assistance | $4,959,635 | $5,024,386 | 336 | $105.5M | Research |
| Ethan Allen Personnel Group, Inc. | Administrative and Support and Waste Management | $3,481,150 | $0 | 430 | $67.7M | Research |
| Chazen Engineering, Land Surveying & Landscape Architecture | Professional, Scientific, and Technical Services | $2,873,635 | $2,905,645 | 168 | $20.7M | Research |
| Orthopedic Associates of Dutchess County, PC | Health Care and Social Assistance | $2,856,238 | $2,894,504 | 240 | $75.3M | Research |
| The Children's Home of Poughkeepsie, | Health Care and Social Assistance | $2,618,700 | $2,655,290 | 305 | N/A | Research |
| Hudson Valley Hospice, INC | Health Care and Social Assistance | $2,476,700 | $2,506,692 | 206 | N/A | Research |
| Key Construction Services LLC | Construction | $2,174,522 | $2,217,655 | 85 | $21.5M | Research |
| Family Services, INC | Health Care and Social Assistance | $2,154,937 | $2,179,911 | 182 | N/A | Research |
| The Children's Home of Poughkeepsie N.y. | Health Care and Social Assistance | $2,000,000 | $2,028,110 | 270 | N/A | Research |
| Lcs Companies of New York, Inc. | Administrative and Support and Waste Management | $1,855,300 | $1,879,089 | 326 | $70.6M | Research |
| Lutheran Center at Poughkeepsie, Inc. | Health Care and Social Assistance | $1,846,300 | $1,866,635 | 495 | $84.2M | Research |
| Mpi Incorporated | Manufacturing | $1,636,233 | $1,650,264 | 82 | $21.5M | Research |
| Efco Products INC | Manufacturing | $1,604,557 | $1,628,120 | 89 | $31.4M | Research |
| Efco Products Inc. | Manufacturing | $1,604,500 | $1,617,292 | 79 | $27.9M | Research |
| The Children's Medical Group Pllc | Health Care and Social Assistance | $1,596,337 | $1,610,813 | 85 | $26.7M | Research |
| The Children's Medical Group Pllc | Health Care and Social Assistance | $1,596,337 | $1,611,207 | 122 | $38.3M | Research |
| Dutchess Beer Distributors, Inc. | Wholesale Trade | $1,583,400 | $1,595,200 | 120 | $30.9M | Research |
| Dutchess Cars, LLC | Retail Trade | $1,549,000 | $1,566,272 | 114 | $28.7M | Research |
| Etny LLC | Health Care and Social Assistance | $1,492,160 | $1,504,915 | 197 | $45.6M | Research |
| Etny LLC | Health Care and Social Assistance | $1,490,000 | $1,495,388 | 181 | $41.9M | Research |
| Hudson Valley Radiologists, P.c. | Health Care and Social Assistance | $1,349,422 | $1,365,726 | 72 | $16.7M | Research |
| Mueller-Phipps International | Manufacturing | $1,346,247 | $1,358,935 | 113 | $29.6M | Research |
| Schatz Bearing Corporation | Manufacturing | $1,215,680 | $1,227,456 | 75 | $18.3M | Research |
| Schatz Bearing Corporation | Manufacturing | $1,215,600 | $1,226,590 | 126 | $30.8M | Research |