| Children's Home of Jefferson County | Health Care and Social Assistance | $3,142,518 | $3,178,850 | 232 | N/A |  Research |
| Renzi Bros., Inc. | Wholesale Trade | $2,847,092 | $2,879,385 | 193 | $49.7M | Research |
| Purcell Construction Corp. | Construction | $2,102,530 | $2,126,493 | 109 | $124.2M | Research |
| The Stebbins Engineering and Manufacturing Company | Construction | $2,077,620 | $2,099,705 | 199 | $46.0M | Research |
| Renzi Bros. Inc. | Wholesale Trade | $2,000,000 | $2,011,342 | 220 | $56.6M | Research |
| Johnson Newspaper Corporation | Information | $2,000,000 | $1,986,870 | 208 | $34.9M | Research |
| Bernier, Carr & Associates, Engineers, Architects and Land S | Professional, Scientific, and Technical Services | $1,632,853 | $1,644,081 | 93 | $11.5M | Research |
| Johnson Newspaper Corporation | Information | $1,500,000 | $1,512,205 | 243 | $40.8M | Research |
| Jefferson Anesthesiologist Services, P.c. | Health Care and Social Assistance | $1,372,490 | $859,012 | 19 | $6.0M | Research |
| North Country Family Health Center Inc. | Health Care and Social Assistance | $1,369,739 | $1,384,112 | 134 | N/A | Research |
| North Country Family Health Center Inc. | Health Care and Social Assistance | $1,369,739 | $1,386,438 | 134 | N/A | Research |
| Hi-Lite Airfield Services, LLC | Construction | $1,335,250 | $1,343,150 | 84 | $26.0M | Research |
| Samaritan Medical Practice, P.c. | Health Care and Social Assistance | $1,129,130 | $1,144,969 | 90 | $16.4M | Research |
| Samaritan Medical Practice PC | Health Care and Social Assistance | $1,129,130 | $1,134,729 | 90 | $28.2M | Research |
| Credo Community Center for Treatment of Addictions, Inc. | Health Care and Social Assistance | $1,100,000 | $1,107,836 | 137 | N/A | Research |
| North Country Orthopaedic Group, P.c | Health Care and Social Assistance | $1,034,878 | $1,046,219 | 147 | $46.1M | Research |
| Disabled Persons Action Organization Inc. | Health Care and Social Assistance | $943,400 | $950,766 | 246 | N/A | Research |
| North Country Transitional Living Services, Inc. | Health Care and Social Assistance | $925,000 | $930,094 | 151 | N/A | Research |
| Hyde-Stone Mechanical Contractors Holding Co., Inc. | Construction | $897,407 | $908,791 | 56 | $17.7M | Research |
| Fx Caprara Cdjr of Watertown LLC | Retail Trade | $808,000 | $815,416 | 79 | $19.9M | Research |
| White's Lumber, Inc. | Retail Trade | $772,292 | $780,311 | 80 | $16.5M | Research |
| F.x. Caprara Auto Sales Inc. | Retail Trade | $719,713 | $727,580 | 68 | $17.1M | Research |
| F.x. Caprara Auto Sales, Inc. | Retail Trade | $719,713 | $725,687 | 68 | $17.1M | Research |
| Cornell Cooperative Extension Association of Jefferson Count | Educational Services | $715,658 | $693,027 | 70 | N/A | Research |
| The Young Christian Mens Association of Watertown NY Inc. | Health Care and Social Assistance | $694,895 | $698,731 | 140 | $22.7M | Research |