| F.g. Downing Development, INC | Retail Trade | $900,000 | $909,962 | 151 | $38.1M | AI Deep Dive |
| Broetje Automation USA Inc. | Manufacturing | $899,700 | $906,257 | 55 | $14.4M | AI Deep Dive |
| Mb of Buffalo | Retail Trade | $897,045 | $905,499 | 86 | $21.7M | AI Deep Dive |
| Iskalo 5000 Main LLC | Accommodation and Food Services | $891,691 | $901,609 | 223 | $69.7M | AI Deep Dive |
| Wha Two, LLC | Retail Trade | $870,087 | $879,980 | 67 | $16.9M | AI Deep Dive |
| Dave Smith Ford | Wholesale Trade | $865,405 | $868,890 | 65 | $19.9M | AI Deep Dive |
| Transitowne Dodge Associates LP | Retail Trade | $864,257 | $875,409 | 117 | $29.5M | AI Deep Dive |
| St. Gregory the Great | Other Services (except Public Administration) | $816,025 | $821,592 | 97 | $18.5M | AI Deep Dive |
| Iskalo 5000 Main, LLC | Accommodation and Food Services | $795,500 | $805,220 | 147 | $46.0M | AI Deep Dive |
| Northtown Transit, LLC | Retail Trade | $786,070 | $795,008 | 72 | $18.1M | AI Deep Dive |
| Giancarlo's Walker Center, LLC | Accommodation and Food Services | $740,515 | $748,711 | 86 | $15.3M | AI Deep Dive |
| Cappellino Cadillac, Inc. | Unknown | $722,690 | $732,134 | 45 | N/A | AI Deep Dive |
| Haley Marketing Group INC | Professional, Scientific, and Technical Services | $717,160 | $723,781 | 46 | <$5M | AI Deep Dive |
| Iskalo Development Corp. | Real Estate and Rental and Leasing | $706,455 | $712,416 | 223 | $33.5M | AI Deep Dive |
| Iskalo Development Corp | Real Estate and Rental and Leasing | $695,215 | $703,348 | 48 | $7.2M | AI Deep Dive |
| Carstar Eastern Hills LLC | Other Services (except Public Administration) | $669,055 | $674,572 | 43 | $8.4M | AI Deep Dive |
| The Original Pancake House of Williamsville Inc. | Accommodation and Food Services | $651,591 | $660,035 | 96 | $17.0M | AI Deep Dive |
| Summit Services Unlimited INC | Wholesale Trade | $631,500 | $638,023 | 293 | $75.4M | AI Deep Dive |
| Buf Foods LLC | Accommodation and Food Services | $615,300 | $620,020 | 252 | $44.7M | AI Deep Dive |
| Alternative Collections, LLC | Administrative and Support and Waste Management | $603,775 | $609,532 | 28 | $5.3M | AI Deep Dive |
| Santoras Phase II LLC | Accommodation and Food Services | $592,655 | $601,380 | 183 | $32.5M | AI Deep Dive |
| Mason Wireless Solutions Ltd. | Construction | $589,900 | $594,781 | 33 | $10.9M | AI Deep Dive |
| Heathwood Assisted Living at Williamsville, Inc. | Health Care and Social Assistance | $579,185 | $585,659 | 52 | $8.8M | AI Deep Dive |
| Selective Staffing Solutions | Administrative and Support and Waste Management | $563,500 | $501,823 | 25 | <$5M | AI Deep Dive |
| Cloud Resources Staffing, LLC | Professional, Scientific, and Technical Services | $563,279 | $568,974 | 27 | $5.6M | AI Deep Dive |