| Haywood Pediatric & Adolescent | Health Care and Social Assistance | $417,500 | $422,853 | 32 | $10.0M |  Research |
| Bodnar & Wyatt, Pllc | Health Care and Social Assistance | $367,137 | $371,879 | 35 | $8.1M | Research |
| Bodnar & Wyatt Pllc | Health Care and Social Assistance | $364,129 | $366,061 | 39 | $9.0M | Research |
| Rsh Inc. | Retail Trade | $356,000 | $360,535 | 40 | $12.2M | Research |
| Midway Medical Center P.a. | Health Care and Social Assistance | $348,400 | $352,667 | 32 | $10.0M | Research |
| Mountain Eye Associates Pllc | Health Care and Social Assistance | $288,803 | $290,243 | 27 | $8.5M | Research |
| Western Australian Holdings LLC | Agriculture, Forestry, Fishing and Hunting | $212,500 | $0 | 30 | <$5M | Research |
| Haywood Medical Imaging, P.c. | Health Care and Social Assistance | $212,425 | $214,903 | 7 | <$5M | Research |
| Southern Appalachian Grading & Excavation, Inc. | Construction | $208,647 | $211,682 | 16 | <$5M | Research |
| Industrial Contractors of Carolina, Inc. | Construction | $204,003 | $207,099 | 25 | $28.5M | Research |
| Mountain Laurel Dermatology Pllc | Health Care and Social Assistance | $172,000 | $173,132 | 12 | <$5M | Research |
| Mce Ventures, LLC | Administrative and Support and Waste Management | $146,700 | $147,821 | 44 | $8.3M | Research |
| John M. Highsmith, D.d.s., P.a. | Health Care and Social Assistance | $146,132 | $147,898 | 8 | <$5M | Research |
| Envision Pain Management Pllc | Health Care and Social Assistance | $129,600 | $126,511 | 12 | <$5M | Research |
| Shawn R. Kennedy DDS Ms & James C Ewing | Health Care and Social Assistance | $119,312 | $120,472 | 9 | <$5M | Research |
| Thunder Contracting, Inc. | Construction | $114,400 | $115,274 | 7 | <$5M | Research |
| Teague & Van Praag DDS Pllc | Health Care and Social Assistance | $92,600 | $93,716 | 10 | <$5M | Research |
| Teague & Van Praag DDS Pllc | Health Care and Social Assistance | $92,000 | $93,182 | 11 | <$5M | Research |
| Aspire Youth & Family, INC | Health Care and Social Assistance | $90,900 | $92,088 | 26 | N/A | Research |
| Ramellini Associates, P.c. | Health Care and Social Assistance | $89,600 | $90,710 | 7 | <$5M | Research |
| Ramellini Associates P.c. | Health Care and Social Assistance | $85,900 | $86,983 | 8 | <$5M | Research |
| James C Ewing DDS PA | Health Care and Social Assistance | $85,884 | $56,931 | 4 | <$5M | Research |
| Country Lane Animal Hospital P.a. | Professional, Scientific, and Technical Services | $84,300 | $85,355 | 7 | <$5M | Research |
| Blue Ridge Dermatology, P.a. | Health Care and Social Assistance | $78,532 | $79,335 | 9 | <$5M | Research |
| Affordable Cleaning of Wnc | Retail Trade | $75,000 | $62,870 | 15 | <$5M | Research |