| Doctors Making Housecalls-Family Medicine | Health Care and Social Assistance | $345,306 | $350,509 | 17 | $5.3M | AI Deep Dive |
| Triangle Community Foundation | Other Services (except Public Administration) | $344,539 | $347,456 | 19 | N/A | AI Deep Dive |
| Best Wireless 1 INC | Information | $343,827 | $348,801 | 105 | $17.6M | AI Deep Dive |
| Institute for the Development of Young Leaders | Educational Services | $342,315 | $347,440 | 44 | N/A | AI Deep Dive |
| Ladybird LLC | Accommodation and Food Services | $342,008 | $345,276 | 25 | <$5M | AI Deep Dive |
| Sushinara Inc. | Accommodation and Food Services | $341,947 | $344,968 | 80 | $14.2M | AI Deep Dive |
| Craftsmanship Installations INC | Construction | $341,042 | $342,274 | 25 | $7.9M | AI Deep Dive |
| Upward Change Health Services, LLC | Health Care and Social Assistance | $340,965 | $344,253 | 46 | $10.7M | AI Deep Dive |
| The North Carolina Coalition Against Domestic Violence, Inc. | Health Care and Social Assistance | $338,800 | $342,360 | 28 | N/A | AI Deep Dive |
| Processmaker INC | Wholesale Trade | $338,500 | $340,888 | 23 | $7.0M | AI Deep Dive |
| Elmo's Diner Inc. | Accommodation and Food Services | $337,800 | $339,971 | 75 | $13.3M | AI Deep Dive |
| Bridgepoint General Contracting INC | Construction | $337,590 | $340,066 | 18 | $20.5M | AI Deep Dive |
| Bridgepoint General Contracting Inc. | Construction | $337,500 | $339,853 | 19 | $21.6M | AI Deep Dive |
| Durham Central Market, Inc. | Retail Trade | $337,460 | $340,770 | 39 | $9.7M | AI Deep Dive |
| Student U | Other Services (except Public Administration) | $336,840 | $339,627 | 32 | N/A | AI Deep Dive |
| Crocodile Creek INC | Wholesale Trade | $335,891 | $338,671 | 21 | $6.4M | AI Deep Dive |
| Crocodile Creek Inc. | Wholesale Trade | $335,800 | $313,829 | 22 | $6.7M | AI Deep Dive |
| Hope Valley Diner & Catering INC | Accommodation and Food Services | $335,000 | $338,871 | 58 | $10.3M | AI Deep Dive |
| Upward Change Health Services LLC | Health Care and Social Assistance | $333,947 | $336,509 | 42 | $7.5M | AI Deep Dive |
| Horizon Video Productions Inc. | Information | $333,900 | $336,013 | 19 | <$5M | AI Deep Dive |
| Radcom Software Services LLC | Professional, Scientific, and Technical Services | $333,122 | $326,433 | 30 | $6.2M | AI Deep Dive |
| Trc Construction, Inc. | Construction | $332,600 | $336,801 | 31 | $9.4M | AI Deep Dive |
| Opans LLC | Health Care and Social Assistance | $332,100 | $333,738 | 15 | <$5M | AI Deep Dive |
| Carolina Theatre of Durham INC | Arts, Entertainment, and Recreation | $331,700 | $334,003 | 77 | N/A | AI Deep Dive |
| Motorco LLC | Accommodation and Food Services | $330,369 | $332,516 | 19 | <$5M | AI Deep Dive |