| Palziv North America, Inc. | Agriculture, Forestry, Fishing and Hunting | $1,816,250 | $1,774,785 | 182 | $9.1M |  Research |
| Louisburg College Inc. | Educational Services | $1,145,700 | $1,154,740 | 177 | $21.2M | Research |
| Louisburg College, Inc. | Educational Services | $1,119,100 | $1,129,984 | 226 | $27.1M | Research |
| East Coast Drilling & Blasting, Inc. | Construction | $978,300 | $984,659 | 96 | $36.0M | Research |
| Toney Lumber Company INC | Retail Trade | $551,600 | $555,477 | 90 | $18.6M | Research |
| Triangle Insurance & Associates, LLC | Finance and Insurance | $425,600 | $409,330 | 37 | $19.0M | Research |
| Lake Royale Property Owners Association | Other Services (except Public Administration) | $304,885 | $307,491 | 28 | N/A | Research |
| Kcbo LLC | Accommodation and Food Services | $237,392 | $238,876 | 22 | <$5M | Research |
| Wester Farms Agricultural Transport LLC | Transportation and Warehousing | $232,900 | $238,356 | 20 | $5.3M | Research |
| L. H. Dickens & Son Inc. | Wholesale Trade | $232,200 | $234,897 | 21 | $5.4M | Research |
| L H Dickens & Son INC | Wholesale Trade | $216,900 | $218,974 | 23 | $5.9M | Research |
| Logan Cattle Co LLC | Agriculture, Forestry, Fishing and Hunting | $214,152 | $178,872 | 26 | <$5M | Research |
| Logan Cattle Co LLC | Agriculture, Forestry, Fishing and Hunting | $214,152 | $198,700 | 26 | <$5M | Research |
| True Work Inc. | Construction | $213,000 | $215,503 | 22 | $8.2M | Research |
| Backyard Leisure LLC | Retail Trade | $206,000 | $208,054 | 31 | <$5M | Research |
| Kcbo Inc. | Accommodation and Food Services | $168,400 | $170,052 | 22 | <$5M | Research |
| Jimmy D. Nelms Logging Inc. | Agriculture, Forestry, Fishing and Hunting | $161,300 | $162,639 | 19 | <$5M | Research |
| Impact Healthcare PA | Health Care and Social Assistance | $152,700 | $154,015 | 19 | <$5M | Research |
| Tcc Enterprises, Inc. | Construction | $152,000 | $152,768 | 15 | $17.1M | Research |
| Johnny Bulls Steakhouse LLC | Accommodation and Food Services | $148,921 | $149,683 | 29 | $5.1M | Research |
| Griffin Ford Inc. | Retail Trade | $145,900 | $147,531 | 10 | <$5M | Research |
| Johnny Bull's Steakhouse LLC | Accommodation and Food Services | $138,600 | $139,736 | 29 | $5.1M | Research |
| Southern Rigging and Erection of Louisburg, Incorporated | Construction | $136,285 | $137,792 | 11 | <$5M | Research |
| Bunn Heating and Air Cond INC | Construction | $135,400 | $136,724 | 11 | <$5M | Research |
| Dr James G Hardy | Health Care and Social Assistance | $130,905 | $132,883 | 14 | <$5M | Research |