| Hot Springs Health Program, INC | Health Care and Social Assistance | $1,373,500 | $1,387,502 | 121 | N/A | Research |
| Asheville Kombucha Mamas, LLC | Manufacturing | $617,400 | $621,866 | 96 | $33.9M | Research |
| Wilkinson Care Center, Inc. | Health Care and Social Assistance | $564,500 | $569,549 | 93 | $15.8M | Research |
| French Broad Paving Inc. | Construction | $133,600 | $134,205 | 14 | <$5M | Research |
| French Broad Rafting and Ziplines LLC | Arts, Entertainment, and Recreation | $93,265 | $93,924 | 84 | $11.8M | Research |
| French Broad Rafting and Ziplines LLC | Arts, Entertainment, and Recreation | $93,265 | $93,768 | 63 | $8.8M | Research |
| Original Look LLC | Other Services (except Public Administration) | $87,200 | $87,900 | 8 | <$5M | Research |
| Madison County Community Learning Centers | Educational Services | $82,800 | $83,437 | 21 | N/A | Research |
| Original Look LLC | Other Services (except Public Administration) | $78,300 | $78,931 | 8 | <$5M | Research |
| J G Ramsbottom III Dmd PA | Health Care and Social Assistance | $71,300 | $71,722 | 7 | <$5M | Research |
| Dream Escapes Landscape and Design LLC | Professional, Scientific, and Technical Services | $66,096 | $66,797 | 8 | <$5M | Research |
| Triple C - Chandley Farms, Inc. | Agriculture, Forestry, Fishing and Hunting | $62,500 | $63,108 | 3 | <$5M | Research |
| Construction & Landscape Services, INC | Administrative and Support and Waste Management | $58,600 | $59,145 | 6 | <$5M | Research |
| Madison Pharmacy & Gifts, Inc. | Retail Trade | $58,000 | $58,559 | 5 | <$5M | Research |
| Mcsono, LLC | Accommodation and Food Services | $56,244 | $56,585 | 4 | <$5M | Research |
| Sandy Bottom Trail Rides LLC | Arts, Entertainment, and Recreation | $54,300 | $54,653 | 25 | <$5M | Research |
| Sandy Bottom Trail Rides LLC | Arts, Entertainment, and Recreation | $54,300 | $54,697 | 25 | <$5M | Research |
| Smokey Mountain Diner LLC | Accommodation and Food Services | $52,500 | $52,917 | 16 | <$5M | Research |
| Earthcast Technologies | Professional, Scientific, and Technical Services | $52,400 | $53,029 | 12 | <$5M | Research |
| Red Shed Woodworks and Construction, INC | Manufacturing | $49,576 | $49,909 | 4 | <$5M | Research |
| Red Shed Woodworks and Construction INC | Construction | $48,493 | $48,785 | 4 | <$5M | Research |
| Hoeh Works INC | Manufacturing | $47,318 | $47,996 | 6 | <$5M | Research |
| Slam Truck and Trailer LLC | Other Services (except Public Administration) | $42,908 | $43,131 | 4 | <$5M | Research |
| Sharpe & Bowman Pllc | Professional, Scientific, and Technical Services | $42,470 | $42,856 | 4 | <$5M | Research |
| Walnut Service Center, Inc. | Other Services (except Public Administration) | $42,100 | $42,554 | 5 | <$5M | Research |